research Industry update: the latest developments in the field of therapeutic delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
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930-960 / 1000+ results research Chronological clinicopathological characterization of rapidly progressive alopecia areata resistant to multiple i.v. corticosteroid pulse therapies: An implication for improving the efficacy
Current corticosteroid pulse therapy is not very effective for severe rapidly progressive alopecia areata.
research Alopecia areata mit gutem Ansprechen auf Tofacitinib
Tofacitinib helped regrow hair in a woman with alopecia areata.
research A comprehensive review of platelet-rich plasma for the treatment of dermatologic disorders
Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.
research Topical latanoprost acid for female androgenetic alopecia: a pilot proof-of-concept trial with mechanistic evidence of FP-receptor activation
Topical latanoprost acid at 0.05% concentration improved hair growth in women with androgenetic alopecia.
research PULSED ADMINISTRATION OF CORTICOSTEROIDS IN THE TREATMENT OF ALOPECIA AREATA
A 300 mg monthly pulse of prednisolone effectively and safely treats widespread alopecia areata.
research 376 Tsc2 disruption in mesenchymal progenitors regulates hair follicles and TGF beta signaling
Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.
research Comparison of the Efficacy of Topical Methotrexate 1% gel Versus Topical Betamethasone Dipropionate 0.05% Lotion in the Treatment of Localized Scalp Alopecia Areata in a Tertiary Care Institute of Central India: A Randomized Control Trial
Both treatments work equally well for hair regrowth, but the lotion has fewer side effects.
research Translational Positioning of Janus Kinase (JAK) Inhibitors in Alopecia Areata
JAK inhibitors may help treat Alopecia Areata but need careful monitoring due to side effects.
research The application of platelet-rich plasma in the treatment of androgenic alopecia
PRP injections effectively improve hair growth in androgenic alopecia.
research Commentary on Platelet-Rich Plasma for Androgenetic Alopecia
PRP injections may improve hair loss condition, but more research needed.
research Targeting the Hippo/YAP /TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research Stimulation of elastin expression by minoxidil in chick skin fibroblasts
Minoxidil boosts elastin production, potentially helping skin diseases.
research Ανάπτυξη καινοτόμων πεπτιδικών φορέων με ιδιότητες αυτοσυναρμογής για τοπική χορήγηση φαρμάκων
Self-assembling peptide hydrogels effectively deliver drugs locally, enhancing treatment and reducing side effects.
research FOCAL HYPERTRICHOSIS DURING TOPICAL TACROLIMUS THERAPY FOR CHILDHOOD VITILIGO
An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
research Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetradecanoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate
TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.
research ANTI-INFLAMMATORY ACTIVITY OF PLATELET-RICH PLASMA TREATMENT IN THE INFLAMMATION MANAGEMENT OF KNEE OSTEOARTHRITIS: EXPERIMENTAL STUDY
Platelet-rich plasma treatments reduce knee osteoarthritis inflammation, with pure PRP being more effective.
research Apremilast treatment of atopic dermatitis and other chronic eczematous dermatoses
Apremilast improved symptoms in patients with severe skin conditions.
research Inhibition of prolactin promotes secondary skin follicle activation in cashmere goats
Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.
research Contribution à l'étude du lien entre Annonaceae et parkinsonisme : identification et quantification d'acétogénines par déréplication; métabolisation de phase I et approche de la distribution de l'annonacine
Thymosin β4 helps with healing, inflammation, and organ protection.
research Trans-Epidermal Elimination Due to Insulin Formulation: Report of a Rare Adverse Effect
Switching insulin brands caused skin lesions in a diabetic woman, resolved by changing to oral medication.
research Using automated microneedling with platelet rich plasma for treating cicatricial alopecia, recalcitrant alopecia areata and traction alopecia, case report
Microneedling with platelet-rich plasma can improve different types of hair loss.
research Randomized controlled trial on a PRP-like cosmetic, biomimetic peptides based, for the treatment of alopecia areata
The PRP-like cosmetic with biomimetic peptides is potentially effective and safe for treating alopecia areata.
research Extensive donor site keloids in follicular unit extraction hair transplantation
Hair transplant can cause hard-to-treat keloids in some patients.
research Severe scalp hair loss in a female patient with acromegaly treated with lanreotide autogel after unsuccessful surgery
A woman with acromegaly experienced severe hair loss from a drug called Lanreotide Autogel, which improved after stopping the treatment.
research JAK Family Expression and Therapeutic Implications in Primary Cicatricial Alopecias
JAK inhibitors may help treat certain types of hair loss, but more research is needed.
research AMERICAN SOCIETY FOR DERMATOLOGIC SURGERY, INC.
New techniques and findings in dermatologic surgery show improved pain management, safer liposuction, better hair transplantation, and effective treatments for skin conditions.
research [Influence and mechanism of extracellular vesicles derived from human dermal papilla cells on skin fibrosis in mice].
Human dermal papilla cell vesicles can reduce skin fibrosis in mice.
research 14 Dermatological drugs, topical agents, and cosmetics
Dermatological treatments can have significant side effects, including allergic reactions, sexual dysfunction, and increased cancer risk.
research Emerging Topical and Systemic JAK Inhibitors in Dermatology
JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.