research Specific inhibition of FGF5-induced cell proliferation by RNA aptamers
RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
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390-420 / 938 results research Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli
A stable, active version of a growth factor was made in bacteria, showing promise for medical use.
research Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene
A mouse gene mutation increases the risk of skin cancer.
research A Case of Tricho-rhino-phalangeal Syndrome Caused by a Novel Heterozygous Nonsense Mutation in the TRPS1 Gene
A new mutation in the TRPS1 gene caused Trichorhinophalangeal syndrome in a 17-year-old, highlighting the need for genetic testing.
research Mice with Alopecia, Osteoporosis, and Systemic Amyloidosis Due to Mutation in Zdhhc13, a Gene Coding for Palmitoyl Acyltransferase
A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
research Diagnostic Exercise: Severe Bilaterally Symmetrical Alopecia in a Horse
A horse with severe hair loss was diagnosed with alopecia areata and a yeast infection.
research Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice.
Lack of KSR1 stops certain skin tumors in mice.
research Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research Skin tissue engineering
Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
research Normal head-hair length is correlated with its diameter
Hair length and thickness are related, with thickness peaking at about a quarter of the hair's maximum length.
research The genetics of hair shaft disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Hair cycle control by leptin as a new anagen inducer
Leptin, a hormone, is important for starting hair growth.
research Measurement of hair growth
Scalp hair grows at 0.37 mm/day, forearm hair at 0.18 mm/day, and thigh hair at 0.30 mm/day, with no significant differences found in people with certain hair conditions.
research Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli
KGF-1 135 is a stable and effective alternative for treating oral mucositis.
research Break Dancing: A New Risk Factor for Scarring Hair Loss
Break dancing on the head may cause a type of scarring hair loss that needs early treatment to prevent permanent damage.
research Minoxidil improved hair density in an Asian girl with short anagen syndrome: a case report and review of literature
Minoxidil treatment increased hair density in a young Asian girl with short anagen syndrome, but didn't improve hair length or thickness.
research Independent DSG4 frameshift variants in cats with hair shaft dystrophy
Cats with abnormal hair had DSG4 gene changes causing hair problems.
research Genetics of Structural Hair Disorders
The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.
research Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness
The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.
research A function for Rac1 in the terminal differentiation and pigmentation of hair
Rac1 is essential for proper hair structure and color.
research Clinical and molecular genetic studies in hereditary hair loss
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
research Discussion: Themes in the Molecular Structure of Hair
Keratin proteins are crucial for hair structure and strength.
research Mutations in the Keratin 85 (KRT85/hHb5) Gene Underlie Pure Hair and Nail Ectodermal Dysplasia
Mutations in the KRT85 gene cause hair and nail problems.
research Smoothened antagonists for hair inhibition
Two new compounds were found to effectively reduce hair growth in mice.
research Cortisol levels in blood and hair of unanesthetized grizzly bears (Ursus arctos) following intravenous cosyntropin injection
Injecting cosyntropin into grizzly bears increases blood cortisol but doesn't change hair cortisol levels.
research Cryogelation of human hair keratins
Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.
research Hair Loss: A Harbinger of the Morbidities to Come!
Early hair loss in men and women may indicate a higher risk of heart disease and metabolic problems.
research Diversity of vibrissal follicle anatomy in cetaceans
Different whale and dolphin species have unique whisker follicle structures, suggesting they might use their whiskers in various ways.
research Common causes of hair loss – clinical manifestations, trichoscopy and therapy
The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.
research Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.