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$Management of a Refractory EIF3E-RSPO2 Fusion Positive Pilomatrical Cancer Patient with Encyclopedic Tumor Analysis Guided Treatment$

research Management of a Refractory EIF3E-RSPO2 Fusion Positive Pilomatrical Cancer Patient with Encyclopedic Tumor Analysis Guided Treatment

September 2020 in “Acta Scientific Cancer Biology”

Personalized treatment based on detailed tumor analysis successfully managed and reduced the patient's aggressive hair follicle cancer.

research Commentary on BRCA1-Associated Protein-1 Tumor Predisposition Syndrome in a Patient With Numerous Basal Cell Carcinomas

January 2019 in “Dermatologic Surgery”

research The role of Pygo2 during intestinal tumor initiation and progression in vivo

January 2016

Pygo2 is important for early growth and progression of intestinal tumors, and could be a target for treating cancers with certain mutations.

A New Way to Restore Tumor Suppressor Function

research A new way to restore tumour suppressor function

August 2013 in “Nature Reviews Drug Discovery”

New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.

research Role of the bone morphogenetic protein signalling in skin carcinogenesis. Effect of transgenic overexpression of BMP antognist Noggin on skin tumour development; molecular mechanisms underlying tumour suppressive role of the BMP signalling in skin.

January 2009 in “Bradford Scholars (University of Bradford)”

BMP signaling helps prevent skin tumors by blocking cancer-promoting pathways.

research Hair sheath keratins in follicular tumors. (5). Identification of hair sheath keratins in keratoacanthoma; Histopathological hair sheath structures in the tumor and their significance as differential histopathological criteria from squamous cell carcinoma.

January 1990 in “The Nishinihon Journal of Dermatology”

Follicular structures help differentiate keratoacanthoma from squamous cell carcinoma.

research A rare case of Leydig cell tumor resulting in female pattern hair loss

January 2019 in “日本皮膚科学会雑誌”

research Basement Membranes in Experimentally Induced Skin Tumors

8 citations , August 1986 in “Journal of Investigative Dermatology”

research TICE salvage chemotherapy treats germ-cell tumors effectively

April 2007 in “Nature Clinical Practice Urology”

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

research Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.

113 citations , May 2002 in “PubMed”

Overexpressing COX-2 in mice skin reduces skin tumor development.

research Trichodiscoma. A Benign Tumor Related to Haarschibe (Hair Disk)

87 citations , August 1974 in “Journal of Investigative Dermatology”

research Immunohistochemical demonstration of breast‐derived and/or carcinoma‐associated glycoproteins in normal skin appendages and their tumors

71 citations , February 1992 in “Journal of Cutaneous Pathology”

Antibodies help identify glycoproteins in normal skin and tumor cells.

Alisertib Is Active as Single Agent in Recurrent Atypical Teratoid Rhabdoid Tumors in Four Children

research Alisertib is active as single agent in recurrent atypical teratoid rhabdoid tumors in 4 children

65 citations , February 2015 in “Neuro-Oncology”

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

research Selenium or No Selenium- That Is the Question in Tumor Patients: A New Controversy

61 citations , May 2010 in “Integrative Cancer Therapies”

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

research Caffeine ameliorates radiation-induced skin reactions in mice but does not influence tumour radiation response

35 citations , February 2002 in “Journal of Radiological Protection”

Caffeine reduces radiation skin damage but doesn't affect tumor treatment.

research Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating

33 citations , May 2018 in “Stem Cell Reports”

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

research Possible Therapeutic Effects of Ozone Mixture on Hypoxia in Tumor Development

25 citations , February 2017 in “Anticancer Research/Anticancer research”

Ozone therapy might improve cancer treatment and reduce its side effects.

research The Effect of Mushroom Beta‐Glucans from Solid Culture of Ganoderma lucidum on Inhibition of the Primary Tumor Metastasis

23 citations , January 2014 in “Evidence-based Complementary and Alternative Medicine”

Mushroom beta-glucans from Ganoderma lucidum can reduce tumor size and metastasis in cancer.

research Isosexual Precocious Pseudopuberty Secondary to a Testosterone-Secreting Leydig Cell Testicular Tumour: True Isosexual Development Early After Surgery*

17 citations , April 2009 in “Andrologia”

A boy's early puberty caused by a testicular tumor returned to normal after surgery.

The Investigation and Management of Severe Hyperandrogenism Pre- and Postmenopause: Non-Tumor Disease Is Strongly Associated with Metabolic Syndrome and Typically Responds to Insulin-Sensitization with Metformin

research The investigation and management of severe hyperandrogenism pre- and postmenopause: Non-tumor disease is strongly associated with metabolic syndrome and typically responds to insulin-sensitization with metformin

14 citations , January 2008 in “Gynecological Endocrinology”

High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.

research A phase I study of MK-5108, an oral aurora A kinase inhibitor, in both monotherapy and in combination with docetaxel in patients with advanced solid tumors.

12 citations , May 2010 in “Journal of Clinical Oncology”

MK-5108 is safe and shows potential against tumors, especially alone.

research Distinct expression profile of stem cell markers, LGR5 and LGR6, in basaloid skin tumors

9 citations , January 2017 in “Virchows Archiv”

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

research Hyperandrogenism Due to a Testosterone-Secreting Sertoli-Leydig Cell Tumor Associated With a Dehydroepiandrosterone Sulfate-Secreting Adrenal Adenoma in a Postmenopausal Woman: Case Presentation and Review of Literature

9 citations , March 2009 in “Endocrine Practice”

research A safety comparative study between freezing nitrogen ethanol composite and liquid nitrogen for cryotherapy of musculoskeletal tumors

7 citations , June 2018 in “Cryobiology”

Freezing nitrogen ethanol composite is safer than liquid nitrogen for treating musculoskeletal tumors.

research Hair shaft miRNA‐221 levels as a new tumor marker of malignant melanoma

7 citations , December 2014 in “Journal of dermatology”

Hair shaft miR-221 levels can help detect malignant melanoma.

research Unusual progression of renal cell carcinoma with carcinomatosis peritoneii and Krukenberg tumour and alopecia with sunitinib therapy in young female

4 citations , February 2018 in “World journal of surgical oncology”

A young woman with kidney cancer experienced rare hair loss from a cancer drug and unusual cancer spread, suggesting early drug treatment might reduce spread and prolong survival.

research Expression of Potential Dermal Progenitor Cell Markers in the Tumour and Stroma of Skin Adnexal Malignant and Benign Tumours

3 citations , April 2019 in “Stem cells international”

Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.

research Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells

3 citations , October 1993 in “Endocrinology”

research Sintilimab-induced Alopecia Universalis in a Patient With the Anti-tumor Effect of Complete Remission After Hepatectomy

2 citations , May 2023 in “Journal of Immunotherapy”

Sintilimab treatment caused hair loss but led to complete tumor remission.

research Seborrheic karatosis, a tumor of the infundibular and isthmus of hair follicles: Identification of hair sheath keratins and histopathological features suggesting hair follicle origin.

2 citations , January 1989 in “The Nishinihon Journal of Dermatology”

Seborrheic keratosis likely originates from the upper regions of hair follicles.

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