research The HPV16 oncogenes cause aberrant stem cell mobilization
HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
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research Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Androgen deprivation therapy and hormonal status in men with COVID-19
Hormonal status from androgen deprivation therapy may affect COVID-19 severity in men.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.
research Ginseng phytochemicals as therapeutics in oncology: Recent perspectives
Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
research Recent Formulation Advances of Mangiferin
Improved delivery methods can enhance mangiferin's effectiveness as a health supplement.
research A review on formulation and analytical aspect of mangiferin a natural phenolic xanthonoid
Improving mangiferin's solubility and delivery can enhance its health benefits.
research Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Severe Unilateral Alopecia in a Long-Term Surviving Male Adolescent Glioblastoma Multiforme Patient
There's an urgent need for better treatments for hair loss caused by radiation therapy.
research Calcineurin-based immunosuppression in renal transplantation : focus on efficacy, the role of steroids, and the cardiovascular risk
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.
research Chemically Induced Depigmentation of Skin and Hair
Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Finasteride inhibits melanogenesis through regulation of the adenylate cyclase in melanocytes and melanoma cells
Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
research Effect of Minoxidil on Cultured Keratinocytes
Minoxidil helps hair cells live longer and grow longer.
research Effects of Hura crepitans and Its Active Ingredient, Daphne Factor F3, on Dihydrotestosterone-Induced Neurotrophin-4 Activation and Hair Retardation
Hura crepitans and its compound daphne factor F3 may help treat hair loss by blocking a specific hair growth inhibitor.
research Onion and leek consumption, garlic supplement use and the incidence of cancer
Eating onions and garlic may have health benefits, but effects vary by type and preparation.
research Classification of Surgical Therapies in Vitiligo
Surgical therapies for vitiligo vary in effectiveness, with combination therapy and medical tattooing recommended for better results.
research Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in mice
Wnt signaling is vital for cell growth, development, and cancer research.
research Defective trophoblast function in mice with a targeted mutation of Ets2
Ets2 gene is crucial for placental development in mice.
research Wnt Signaling in Skin Development, Homeostasis, and Disease
Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
research Medical uses of Carthamus tinctorius L. (Safflower): a comprehensive review from Traditional Medicine to Modern Medicine
More research is needed to confirm safflower's traditional medicinal uses.
research Cell death in the skin
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Role of cholesterol sulfate in epidermal structure and function: Lessons from X-linked ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research Learning from nudity: lessons from the nude phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Beyond Expectations
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Eph/ephrin signaling in epidermal differentiation and disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials
Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Thyroid hormone action in epidermal development and homeostasis and its implications in the pathophysiology of the skin
Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
research Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.