research Data from Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin
Ribonucleotide excision repair is crucial to prevent skin cancer.
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810-840 / 1000+ resultsresearch Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice.
Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.
research Uterus Hyperplasia and Increased Carcinogen-Induced Tumorigenesis in Mice Carrying a Targeted Mutation of the Chk2 Phosphorylation Site in Brca1
Mice with a specific BRCA1 mutation have a higher risk of tumors, especially in the uterus and ovaries.
research 876 Manipulation of stem cell divisional behavior: Selectively promoting asymmetric and symmetric keratinocyte divisions in vitro
Scientists can control how skin stem cells divide by using different treatments.
research The Vitamin D Receptor as Tumor Suppressor in Skin
Vitamin D and its receptor may help prevent skin cancer.
research 859 Building a functional niche for hair follicle stem cells
Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
research A NEW GENERATION OF MARKERS FOR CANCER DETECTION AND DRUG TRANSPORT
New markers can detect tumors, aid drug delivery, and treat cancer effectively and safely.
research Evidence of proliferative activity in human Merkel cells: implications in the histogenesis of Merkel cell carcinoma
research K6/ODC transgenic mice as a sensitive model for carcinogen identification
K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.
research Research advances of tissue-derived extracellular vesicles in cancers
Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.
research EP-2271: The role of mitochondria in the non-targeted effect of ionizing radiation
Mitochondria may influence how cells respond to radiation, affecting nearby non-irradiated cells.
research Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor
Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
research Treg–tissue cell interactions in repair and regeneration
Treg cells help repair and regenerate tissues by interacting with local cells.
research Keloid pathogenesis and fibroproliferative properties are dependent on stem cells regulated by the HEDGEHOG-GLI1 pathway
Blocking the HEDGEHOG-GLI1 pathway can reduce keloid growth and may be a potential treatment.
research 202 Automated assessment of tumor infiltrating lymphocytes informs mortality in thin melanoma
An automated system can predict death risk in thin melanoma by analyzing immune cells.
research Rethinking regeneration: empowerment of stem cells by inflammation
Inflammation helps stem cells repair tissue by directing their behavior.
research Reconstitution of human skin in vitro using readily available sources: Novel studies of tumour promotion
A lab model of human skin was created to study skin tumor promoters without using actual human skin.
research Expression Profiles of Tyrosine Kinases in Cultured Follicular Papilla Cells Versus Dermal Fibroblasts
Certain tyrosine kinases may regulate hair growth and could help develop hair loss treatments.
research Imaging tumor angiogenesis with fluorescent proteins
Fluorescent proteins help visualize and understand tumor blood vessel growth.
research One Transgene: Two Outcomes
Modified β-catenin can cause different effects in mouse skin cells, leading to cysts or tumors depending on the cell type.
research Regulation of self-renewal in colorectal cancer cell models
Reducing SOX2 in colorectal cancer cells decreases tumor growth and self-renewal.
research Antitumor Activities of the Typhonium flagelliforme Extract Combined with Natural Interferons of Canine and Feline in Mice with DMBA Induced Skin Tumors
The combination of Typhonium flagelliforme extract and natural interferons effectively reduces tumor growth in mice.
research 572 Development of immunotherapies targeting TCR-Vβ2 for treatment of cutaneous T cell lymphoma
Targeting TCR-Vβ2 in cutaneous T cell lymphoma shows promise for safer, more specific treatment.
research Faculty Opinions recommendation of Nonviral in situ green fluorescent protein labeling and culture of primary, adult human hair follicle epithelial progenitor cells.
Researchers developed a method to label and study human hair follicle stem cells using a fluorescent protein.
research Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells
Stat3 activation increases hair follicle progenitors but reduces bulge region stem cells.
research 130 Examples of Tumors Diagnosis Via Quantum Resonance Spectrometer
Cancer patients have lower immunity and higher virus and zinc levels in their hair.
research LB1019 The early region of trichodysplasia spinulosa polyomavirus drives proliferation, altered differentiation, and ectopic expression of hair follicle differentiation markers in interfollicular tail epidermis
The early genes of a specific virus can cause abnormal skin cell growth and hair follicle changes.
research Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
research Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas
Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.
research Indian Hedgehog Controls Proliferation and Differentiation in Skin Tumorigenesis and Protects against Malignant Progression
Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.