40 citations
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March 2016 in “The Journal of Clinical Endocrinology & Metabolism” Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.
36 citations
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October 2009 in “Journal of Investigative Dermatology” Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
35 citations
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January 2012 in “The Journal of Sexual Medicine” Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.
32 citations
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May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
3 citations
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January 2016 in “Elsevier eBooks” Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
15 citations
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May 2009 in “Steroids” Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.
14 citations
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June 2011 in “Steroids” New compounds may help treat prostate issues without affecting androgen receptors.
63 citations
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December 2013 in “PLoS ONE” Finasteride may reduce prostate cancer spread by lowering certain enzyme levels.
59 citations
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March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
57 citations
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January 1995 in “The American journal of medicine” Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.
47 citations
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August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
38 citations
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February 2011 in “Annals of Oncology” Men who experienced baldness at age 20 may have double the risk of getting prostate cancer.
11 citations
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January 1991 in “Urology” New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
10 citations
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June 1998 in “International Journal of Dermatology” Inflammation around hair follicles leads to hair loss, and treatments should focus on reducing this inflammation and other factors for effectiveness.
4 citations
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December 2009 in “Elsevier eBooks” Breadfruit is nutritious and has potential health and medicinal benefits, but is currently underused.
3 citations
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November 2020 in “Clinical, Cosmetic and Investigational Dermatology” Early diagnosis and combination therapy, especially with finasteride and dutasteride, are key to managing Frontal Fibrosing Alopecia effectively.
3 citations
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October 2019 in “Dermatologic Therapy” Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
3 citations
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March 2016 in “Phytotherapy Research” The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.
1 citations
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January 2018 in “AUSTRALIAN JOURNAL OF BASIC AND APPLIED SCIENCES” Zapoteca portoricensis extract may help protect against prostate issues and support liver and kidney health in rats.
1 citations
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August 2017 in “The Journal of urology/The journal of urology” 5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.
November 2023 in “Magna Scientia Advanced Research and Reviews” Trazodone might help reverse post finasteride syndrome.
June 2018 in “Global Journal of Reproductive Medicine” Idiopathic hirsutism may be linked to increased skin enzyme activity, and new treatments like laser and eflornithine cream show promise.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
14 citations
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April 2019 in “International Journal of Women's Health” Some treatments can stabilize Frontal Fibrosing Alopecia, but more research is needed to find effective treatments, and hair transplants often fail.
11 citations
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January 2018 in “Asian Journal of Andrology” Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.
3 citations
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April 2010 in “Endocrinology” The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.
1 citations
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July 2018 in “Elsevier eBooks” Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.
2 citations
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June 2022 in “International Journal of Biomedicine” The review suggests a comprehensive approach to treat hirsutism, focusing on hair removal, medication, and managing emotional effects.
June 2025 in “Mağallaẗ ʻulūm al-rāfidayn” New pyrazole derivatives may help treat hair loss, but more testing is needed.