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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Hydrogel microcapsules help create cells that boost hair growth.

Longer anogenital distance may indicate a higher chance of having polycystic ovary syndrome, and measuring this distance along with hormone levels could improve diagnosis.

The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

De nouvelles thérapies promettent de mieux traiter la perte de cheveux due à l'alopécie androgénétique.

The document is a detailed medical reference on skin and genetic disorders.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Securinine and ajmaline may effectively treat liver cancer, with securinine being less toxic to normal cells.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.