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Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride reduces hair growth and is safe for women with excessive hair.

Rats had lasting erectile problems after stopping a certain medication.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

Fenugreek seed extract boosts testosterone and improves male reproductive health without heart side effects.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

Compounds in fluted pumpkin and African yam bean seed oils may help manage benign prostate hyperplasia.

Eclipta alba extract could be a promising natural treatment for hair loss.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

A higher testosterone/dihydrotestosterone ratio in PCOS patients may indicate worse metabolic health.

Finasteride may cause kidney damage.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

Certain Dibenzo derivatives may help treat prostate cancer.

Teak leaf extract can help treat hair loss, and its effectiveness varies by geographic origin.

Finasteride use may increase suicidality risk, especially in young men.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.