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research Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino-Acid Composition and Repeat Structure

51 citations , January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.

research The Hairless Phenotype of the Hirosaki Hairless Rat Is Due to the Deletion of an 80-kb Genomic DNA Containing Five Basic Keratin Genes

35 citations , April 2008 in “Journal of Biological Chemistry”

Hirosaki hairless rats lack hair due to missing DNA with key keratin genes.

research Damage of hair follicle stem cells and alteration of keratin expression in external radiation-induced acute alopecia

28 citations , June 2012 in “International Journal of Molecular Medicine”

Radiation damages hair stem cells and changes keratin expression, with Krt5 as a potential marker for radiation effects.

research Recent advances in preparation and biomedical applications of keratin based biomaterials

9 citations , November 2024 in “Biotechnology for Sustainable Materials”

Keratin-based biomaterials are promising for wound healing, drug delivery, and nerve regeneration due to their biodegradability and biocompatibility.

research Methods of keratin extraction from wool and hair and prospects of their application in biomedicine and bioengineering

1 citations , January 2019 in “Studia Biologica”

Extracted keratin from wool and hair can be used in medicine and bioengineering.

research Adsorption of Diclofenac and PFBS on a Hair Keratin Dimer

December 2023 in “The journal of physical chemistry. B (1997 : Online)”

Human hair keratin might be good for filtering out harmful substances from water.

research Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix

175 citations , August 1997 in “Nature Genetics”

research Novel mutations in the keratin-74 (KRT74) gene underlie autosomal dominant woolly hair/hypotrichosis in Pakistani families

40 citations , December 2010 in “Human Genetics”

research Interleukin-1 Induces Transcription of Keratin K6 in Human Epidermal Keratinocytes

90 citations , February 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Interleukin-1 increases keratin K6 production in skin cells.

research The Intermediate Filament Architecture as Determined by X-Ray Diffraction Modeling of Hard α-Keratin

66 citations , June 2004 in “Biophysical Journal”

Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.

research Hedgehog Signaling, Keratin 6 Induction, and Sebaceous Gland Morphogenesis

33 citations , August 2008 in “American Journal Of Pathology”

Hedgehog signaling is essential for normal sebaceous gland development and affects keratin 6a expression.

research Isolation and Characterization of a Putative Keratin-Associated Protein Gene Expressed in Embryonic Skin of Mice

22 citations , July 1998 in “Journal of Investigative Dermatology”

The 4C32 gene may help in mouse skin development and differentiation.

research Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte

12 citations , December 2011 in “Journal of Dermatological Science”

The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.

research Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells

8 citations , June 2001 in “Journal of Biological Chemistry”

A truncated protein linked to breast cancer may change cell adhesion.

research Structural Transition of Trichocyte Keratin Intermediate Filaments During Development in the Hair Follicle

7 citations , January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry”

research Co-option of Hair Follicle Keratins into Amelogenesis Is Associated with the Evolution of Prismatic Enamel: A Hypothesis

1 citations , October 2017 in “Frontiers in Physiology”

Hair follicle keratin may have been used in tooth enamel evolution.

research Structure and biochemistry of mammalian hard keratin

252 citations , January 1991 in “Electron Microscopy Reviews”

research Alkylation of human hair keratin for tunable hydrogel erosion and drug delivery in tissue engineering applications

75 citations , September 2015 in “Acta biomaterialia”

Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.

research Immunohistochemical demonstration of keratins 8 and 14 in benign tumours of the skin appendage

38 citations , November 1991 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin”

Keratins 8 and 14 can help identify and diagnose benign skin tumors.

research Biochemical and immunohistochemical analyses of keratin expression in basal cell carcinoma

37 citations , May 1998 in “Journal of Dermatological Science”

Basal cell carcinoma shows keratin patterns similar to undifferentiated hair follicle cells.

research Penetration of different molecular weight hydrolysed keratins into hair fibres and their effects on the physical properties of textured hair

7 citations , September 2020 in “International Journal of Cosmetic Science”

Different sizes of keratin peptides can strengthen hair, with smaller ones possibly increasing volume and larger ones repairing damage.

research Hair Keratin

7 citations , January 1990

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