39 citations
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December 2013 in “Phytotherapy Research” Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.
11 citations
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August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
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January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
3 citations
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May 2023 in “Frontiers in immunology” Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
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February 2005 in “Aktuelle Dermatologie” Prolactin and TGF-β receptor blockers might help treat hair loss.
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December 2022 in “Scientific Data” The study maps how genes are regulated during mouse hair growth.
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April 2025 in “Pediatria i Medycyna Rodzinna” Restoring EDA and WNT pathways early may help improve skin, hair, and teeth issues in hypohidrotic ectodermal dysplasia.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dermal EZH2 controls skin cell growth and differentiation in mice.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” Targeting specific cell interactions may help treat skin fibrosis.
16 citations
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January 2016 in “Journal of Investigative Dermatology” Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
44 citations
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March 2004 in “Journal of Investigative Dermatology” The effects of estrogen on human hair growth are unclear and need more research.
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October 2008 in “The American journal of pathology” Blocking a specific protein signal can make hair grow on mouse nipples.
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December 2013 in “Biological & Pharmaceutical Bulletin” Rice bran extract can potentially treat hair loss by promoting hair growth and increasing the number of hair follicles.
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July 2016 in “Elsevier eBooks” Understanding skin structure and development helps diagnose and treat skin disorders.
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February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
391 citations
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January 2010 in “Journal of The American Academy of Dermatology” Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
215 citations
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March 2018 in “Archives of Toxicology” Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
210 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
176 citations
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August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
175 citations
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April 1982 in “Journal of The American Academy of Dermatology” Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.
162 citations
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July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
116 citations
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May 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.
106 citations
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June 2005 in “Journal of Investigative Dermatology” The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.
103 citations
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November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
96 citations
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April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
90 citations
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October 1996 in “Dermatologic Clinics” Growth factors are crucial for hair development and could help treat hair diseases.
86 citations
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April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
78 citations
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February 2011 in “Canadian Medical Association Journal” Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.
64 citations
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November 2012 in “EMBO reports” Lamins are vital for cell survival, organ development, and preventing premature aging.