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A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

Overexpression of hurpin in mice leads to abnormal skin and higher skin cancer risk.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.

Biliverdin IXβ and IXδ help Pseudomonas aeruginosa adapt to chronic infections.

Metabolite 7 is a strong inhibitor for Alzheimer's disease management.

Defective protein folding due to a mutation is key in ANE syndrome.

The agouti gene may help understand and treat obesity.

Selenium in proteins helps prevent over-oxidation and supports chemical reversibility.

Scientists found new, better-working inhibitors for a hormone-related enzyme.

ANE syndrome is caused by a mutation in the RBM28 protein that disrupts ribosome assembly.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.

Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.

New inhibitors may reduce gut toxicity from cancer drugs.

Cathepsin L deficiency causes large, abnormal cell structures and health issues in mice.

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Enzyme presence in hair sheath cells decreases over time, affecting forensic analysis.

The study found a specific peptide that helps detect TGase 3 activity in skin and hair follicles.

Different parts of cells interact at specific areas to control cell functions like energy production and fat storage.

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

UTX is crucial for skin differentiation and health, especially in females.

Changing YBX1 protein activity affects skin stem cell function and aging.

DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.

UVB exposure increases skin proteins for retinoic acid synthesis and shifts their location, possibly affecting skin repair.

The enzyme from Bacillus cereus can be used in detergents and leather processing.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.