research 130 Deciphering the role of the hexosamine pathway in skin homeostasis
The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.
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510-540 / 1000+ resultsresearch Immunohistochemical detection of cytochrome P450 isoenzymes in cultured human epidermal cells.
Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.
research A Mutational Hotspot in the 2B Domain of Human Hair Basic Keratin 6 (hHb6) in Monilethrix Patients
A common mutation in the hHb6 gene is linked to monilethrix, but other factors may also play a role.
research Hair follicle differentiation: expression, structure and evolutionary conservation of the hair type II keratin intermediate filament gene family
Type II keratin genes are crucial for hair follicle differentiation and have a conserved structure and expression pattern.
research Transient expression of keratin 19 is induced in originally negative interfollicular epidermal cells by adhesion of suspended cells.
Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
research Ultrastructural immunolocalization of involucrin in the medulla and inner root sheath of the human hair
Involucrin helps strengthen the inner parts of human hair.
research Collagen-type synthesis in human-hair papilla cells in culture
research Formation of surface membranes in developing mammalian hair fibres
Mature hair surfaces are formed by keratinized cells with developed layers, not just modified plasma membranes.
research The Expression of Vitamin D-Upregulated Protein 1 in Skin and its Interaction with Sciellin in Cultured Keratinocytes
VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.
research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells
Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.
research Epithelial keratin and filaggrin expression in seborrheic keratosis: evaluation based on histopathological classification
Seborrheic keratosis shows varied cell differentiation, and keratin analysis helps diagnose skin tumors.
research Immunogenicity of Hair Proteins Containing Hard Keratins.
Human hair and nail proteins are unlikely to cause allergic reactions.
research α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity
α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
research Novel Type I Hair Keratins K39 and K40 Are the Last to be Expressed in Differentiation of the Hair: Completion of the Human Hair Keratin Catalog
K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.
research A homozygous missense variant in type I keratin KRT25 causes autosomal recessive woolly hair
A genetic variant in the KRT25 gene causes tightly curled hair.
research Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis
Certain mutations in a hair growth-related gene cause a type of genetic hair loss.
research A Review of Keratin-Based Biomaterials for Biomedical Applications
Keratin from hair and wool is used in medical materials for healing and drug delivery.
research Synthesis of porcine pCLCA2 protein during late differentiation of keratinocytes of epidermis and hair follicle inner root sheath
pCLCA2 protein may help maintain skin structure and function.
research [A three-dimensional observation of human hair tissue treated by modified trypsin-HC1 method].
The method allows detailed observation of hair tissue structures.
research Genetics of Structural Hair Disorders
The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.
research Tight junctions form a barrier in porcine hair follicles
Tight junctions create a barrier in pig hair follicles that controls what can enter the skin.
research New keratin isolates: actives for natural hair protection.
Keratin helps protect and strengthen hair, reducing damage and color fading.
research A highly resistant structure between the cuticle and the cortex of human hair. II . CARB , a penetration barrier
CARB is a strong barrier in human hair that prevents dye penetration.
research Histological evaluation of hair keratin based templates in mice
Keratin sponges are as biocompatible as collagen, but keratin gels are slightly less so.
research Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge
The K15 promoter effectively targets stem cells in the hair follicle bulge.
research Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages
Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
research The New Keratin Nomenclature
The keratin naming system was updated to include 54 genes, especially for hair-related keratins.
research Mutation in human hair keratin hHb6 in monilethrix: clinical variation is not due to genetic variation.
research The Fate of Trichohyalin
Trichohyalin is modified by enzymes to form strong structures in hair cells.
research Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles
Human and bovine hair follicles have distinct cytokeratins specific to hair-forming cells.