29 citations
,
January 1998 in “Dermatology” Many acne patients have high androgen levels, which may lead to PCOD, but treatments like oral contraceptives and antiandrogens can help.
February 1996 in “Clinical Pharmacology & Therapeutics” MK-386 reduces sebum DHT levels.
April 2020 in “Journal of the Endocrine Society” A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.
67 citations
,
January 1997 in “Lancet” Hirsutism is when women have too much hair growth, often due to a bit more androgen hormones and sensitive skin.
42 citations
,
December 2015 in “International Journal of Clinical Pharmacology and Therapeutics” The 0.25% finasteride solution, when applied once a day, effectively reduces scalp DHT, potentially minimizing sexual side-effects linked to a systemic DHT reduction.
57 citations
,
January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
46 citations
,
March 2001 in “Journal of endocrinological investigation” 5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
4 citations
,
January 2010 in “Acta dermato-venereologica” Low androgen levels can still cause female pattern hair loss.
3 citations
,
December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.
December 2025 in “Actas Dermo-Sifiliográficas” 16 citations
,
February 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.
5 citations
,
January 1985 in “Archives of Dermatology” Skin creams that block male hormones may help with hair growth, hair loss, and acne.
January 2010 in “Life Science Alliance” Vitamin D receptor is essential for preventing hair loss by regulating hair cycle stages.
7 citations
,
December 2017 in “Journal of the European Academy of Dermatology and Venereology” Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.
17 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” February 2009 in “Endocrinology” DHEA therapy improves pubic hair growth and psychological well-being in girls with central adrenal insufficiency.
23 citations
,
June 2006 in “Journal of Investigative Dermatology” Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.
2 citations
,
February 2019 in “Journal of Investigative Dermatology” Higher levels of the DP2 receptor may lead to hair loss.
98 citations
,
July 1983 in “Journal of Steroid Biochemistry” Individuals with this condition often develop male traits and identities at puberty despite being raised as females.
3 citations
,
November 2005 in “Women's health” Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.
46 citations
,
December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology” Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Hair loss is caused by mechanical, thermal, and metabolic stress, not just hormones.
41 citations
,
March 2016 in “The Journal of Clinical Endocrinology & Metabolism” In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.
28 citations
,
March 2000 in “Obstetrics and gynecology clinics of North America” Hirsutism in teen girls is common, usually harmless, but can sometimes signal serious issues and is treatable.
3 citations
,
August 1986 in “BMJ. British medical journal” Women with excessive hair growth often have hormonal issues and need medical advice and treatment.
November 1971 in “PubMed”
53 citations
,
May 2010 in “Journal of Cellular Physiology” Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.
February 2025 in “Skin Appendage Disorders” Adrenal tumors can cause hair loss and high testosterone in women.
100 citations
,
October 1986 in “Clinical Endocrinology” Alopecia indicates more severe resistance to 1,25-dihydroxyvitamin D.
30 citations
,
April 2011 in “Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry” Analyzing hair with this method can help understand and monitor scalp conditions and treatment effects.