research A model for the turnover of dihydrotestosterone in the presence of the irreversible 5α-reductase inhibitors GI198745 and finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
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research Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia
Finasteride helps hair growth but may cause sexual side effects.
research In Vivo Time-Dependent Inhibition of Human Steroid 5a-Reductase by Finasteride
Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.
research Reply to Effectiveness of dutasteride in a large series of patients with frontal fibrosing alopecia in real clinical practice
Dutasteride can stabilize hair loss in patients with frontal fibrosing alopecia, but its safety in women is unclear, so use it with caution.
research Questionnaire analysis of related factors of male pattern alopecia and clinical efficacy of finasteride therapy in 320 patients
Finasteride effectively treats male pattern hair loss and improves life quality, but psychological support is also recommended.
research Efficacy and safety of topical finasteride spray solution in the treatment of Chinese men with androgenetic alopecia: A phase III, multicenter, randomized, double-blind, placebo-controlled study
Topical finasteride effectively and safely increases hair growth in men with hair loss.
research Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone.
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
research Value of hormonal levels in patients with male androgenetic alopecia treated with finasteride: better response in patients under 26 years old
Finasteride works better for hair loss in patients 26 or younger.
research Sexual dysfunction with 5-alpha-reductase inhibitor therapy for androgenetic alopecia: a global propensity score matched retrospective cohort study
Taking medication for hair loss might cause sexual problems.
research Novel iron oxide nanocarriers loading finasteride or dutasteride: Enhanced skin penetration for topical treatment of alopecia
Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.
research Corrigendum
The 7.1% withdrawal rate was in the oral finasteride group, not the topical one.
research The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia: a systematic review and meta-analysis
Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
research Treatment of postmenopausal frontal fibrosing alopecia with oral dutasteride
Oral dutasteride can potentially treat frontal fibrosing alopecia in postmenopausal women, with some patients showing disease arrest and hair regrowth.
research Finasteride and Erectile Dysfunction in Patients with Benign Prostatic Hyperplasia or Male Androgenetic Alopecia
Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
research ENHANCEMENT OF FINASTERIDE AQUEOUS SOLUBILITY BY NANOSUSPENSION OPTIMIZATION DESIGN
Nanosuspension increased finasteride's water solubility by over 2.5 times.
research Tell me the uses, effectiveness, and adverse effects of topical finasteride in the treatment of androgenetic alopecia.
Topical finasteride effectively treats hair loss with fewer side effects than the oral form.
research Post-Finasteride Syndrome: About 2 Cases and Review of the Literature
research Metabolic effects of 5α-reductase inhibition in humans
Dutasteride may reduce insulin sensitivity and increase body fat.
research The effects of Finasteride on the expression of Dazl, Tsga10, Sycp3, Prm2 genes during spermatogenesis in testes of NMRI mice
Finasteride, at doses of 5mg or higher, may negatively affect male fertility by reducing the expression of certain genes involved in sperm production.
research Post‐finasteride syndrome: real or myth?
Post-finasteride syndrome is rare but serious and should be taken seriously.
research Endocrinology & Metabolism News, August 2005
Finasteride causes temporary cell death in BPH tissues.
research Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia
5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
research Validated RP-TLC Method with Densitometry for Assay of Finasteride in Simple Pharmaceutical Dosage Form
A new, simple, and accurate method was created to measure finasteride in tablets.
research Current Literature Review
The document suggests that finasteride may cause depression and suicidal thoughts, while prostate surgery does not harm sexual health.
research Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
research Finasteride chemoprevention might be cost-effective in high-risk populations
Finasteride may be cost-effective for preventing prostate cancer in high-risk groups.
research 5‐Alpha reductase inhibitors in androgenetic alopecia: Shifting paradigms, current concepts, comparative efficacy, and safety
Dutasteride works better than finasteride for hair loss, with both being safe to use.
research 5 Alpha-reductase inhibitors: whatʼs new?
A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.
research Use of Topical Finasteride Vs Systemic Finasteride in Male Pattern Baldness
Both topical and oral finasteride are equally effective for treating male pattern baldness.
research Level-1 Data From the REDUCE Study and the PCPT Data
Finasteride and dutasteride reduce prostate cancer risk, but finasteride may increase higher-grade cancer risk.