January 2023 in “Vìsnik problem bìologìï ì medicini” Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
192 citations
,
October 1998 in “Experimental Dermatology” Androgenetic alopecia involves complex hair follicle changes and knowledge gaps remain.
May 2023 in “Experimental Dermatology” Male pattern hair loss may be linked to the developmental origins of hair follicles.
6 citations
,
February 2016 in “American Journal of Dermatopathology” The boy with woolly hair nevus had thinner hair and abnormal hair follicles, which improved with treatment but worsened when treatment stopped.
August 2013 in “International Wound Journal” Non-hairy skin cells might be used to regenerate hair, helping with baldness and skin wounds.
19 citations
,
August 1993 in “Journal of Cutaneous Pathology” Alopecia causes smaller hair follicles and affects growth-related structures.
211 citations
,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
235 citations
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January 2011 in “Journal of Clinical Investigation” Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.
April 2016 in “Journal of Investigative Dermatology” Wnt ligands, produced by dermal papilla cells, are essential for adult hair growth and regeneration.
6 citations
,
May 2024 in “Developmental Biology” 38 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Understanding normal hair follicle development helps analyze abnormalities in mutant mice.
February 2023 in “Cosmoderma” An infant with complete hair loss was diagnosed with a genetic disorder affecting hair growth.
25 citations
,
October 1975 in “Journal of Cutaneous Pathology” Hair growth in alopecia areata is hindered due to impaired cell activity in the surrounding tissue.
81 citations
,
January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
1 citations
,
August 1994 in “Journal of Cutaneous Pathology” Hair loss happens due to faster cell growth and fewer cells in affected follicles.
Researchers developed a method to create artificial hair follicles that may help with hair loss treatment and research.
1113 citations
,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
April 2018 in “Journal of Investigative Dermatology” Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.
19 citations
,
August 1996 in “British Journal of Dermatology” Alopecia areata affects hair follicle structure, even in non-balding areas.
A 5-year-old girl has sparse, dry, and brittle hair but is otherwise healthy.
June 2001 in “European Journal of Dermatology” A 54-year-old woman experienced progressive hair loss starting in adolescence, leading to sparse scalp hair and almost no eyebrows or eyelashes.
22 citations
,
April 2015 in “Current problems in dermatology” Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
16 citations
,
January 1998 in “Dermatology” Androgens may worsen a natural hair resting phase, possibly leading to hair loss.
114 citations
,
October 1996 in “Dermatologic clinics” Hair loss is mainly caused by hormones, autoimmune issues, and chemotherapy, and needs more research for treatments.
January 2011 in “Bradford Scholars (University of Bradford)” Testosterone stimulates growth in intermediate hair follicles, but this can be blocked by cyproterone acetate.
41 citations
,
January 2018 in “Advances in experimental medicine and biology”
85 citations
,
February 1989 in “Journal of The American Academy of Dermatology” Children with loose anagen hair have easily pluckable hair due to root sheath problems, and it might improve without treatment.
January 2008 in “Medical Entomology and Zoology” June 2011 in “European Journal of Pediatric Dermatology” An 11-year-old girl with hair thinning was diagnosed with monilethrix and early androgenetic alopecia.
4 citations
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July 2014 in “Journal of Investigative Dermatology” Old people have less hair because their hair follicles don't regenerate as well, not because of fewer stem cells, and a protein called follistatin might help reactivate hair growth.