March 2021 in “AACE clinical case reports” A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.
January 2019 in “Central European Journal of Urology” Testosterone undecanoate can reduce the negative effects of Finasteride on male reproductive health.
July 2020 in “Indian journal of sexually transmitted diseases and AIDS” The document concludes that it's concerning when a teenage boy has both gonorrhea and syphilis at the same time.
43 citations
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January 2006 in “PubMed” Androgens and estrogens are crucial for male reproductive health, affecting hormone levels and tissue function.
5 citations
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December 2004 in “Dermatology” Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.
1 citations
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February 2022 in “Online journal of biological sciences” The document does not determine if adults with aphallia are fertile.
December 1981 in “Pediatric Research”
4 citations
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December 2018 in “Case reports in endocrinology” A 63-year-old woman's male-like symptoms were caused by a rare testosterone-producing ovarian tumor, treated by removing her ovaries and fallopian tubes.
1 citations
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December 2019 in “Frontiers in endocrinology” Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.
19 citations
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March 2004 in “The Journal of Clinical Endocrinology & Metabolism” Testosterone and letrozole treatment speeds up puberty in boys with delayed development.
January 2014 in “European Geriatric Medicine” A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.
October 2023 in “IJEM case reports” A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.
Careful diagnosis is crucial for premature pubarche, as 20% of cases have other conditions.
66 citations
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March 1998 in “Mayo Clinic Proceedings” Removing a testosterone-producing tumor cured a woman's sleep apnea and other symptoms.
January 2025 in “Case Reports in Oncological Medicine” Consider Sertoli-Leydig cell tumors in Peutz-Jeghers syndrome patients with adnexal masses.
April 2020 in “Journal of the Endocrine Society” The patient with a misplaced pituitary gland and interrupted pituitary stalk is being treated with hormone replacement.
Early diagnosis of imperforate hymen is crucial to prevent complications.
11 citations
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September 1990 in “Clinical Endocrinology” Girls with prepubertal simple hypertrichosis have higher dihydrotestosterone (DHT) levels.
2 citations
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June 2023 in “Medicine” A rare skin cancer on a man's elbow was successfully treated with surgery, showing no recurrence after one year.
November 2013 in “The Journal of Urology” 129 citations
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February 2006 in “Andrology” Men with low testosterone should be carefully evaluated and monitored before and during treatment.
9 citations
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January 2007 in “Endocrine Practice” A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.
October 2024 in “Journal of the Endocrine Society” Leydig cell tumors can cause high testosterone and symptoms like hair loss in postmenopausal women, but surgery can improve these symptoms.
January 2003 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Testosterone therapy can improve skin and hair in men with low testosterone but may cause skin irritation with certain treatments.
November 2012 in “Experimental and Clinical Endocrinology & Diabetes” A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.
7 citations
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September 1997 in “PubMed” April 2019 in “Journal of the Endocrine Society” A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
8 citations
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October 2024 in “Frontiers in Cell and Developmental Biology” Telocytes help organize male reproductive tissues and their changes can lead to diseases.
September 2024 in “Medicine theory and practice” A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.