788 citations
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February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
344 citations
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June 2006 in “American Journal Of Pathology” Human hair follicles can provide stem cells for regenerative medicine.
113 citations
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June 2015 in “Stem Cell Research & Therapy” Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
22 citations
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March 2023 in “Bioengineering” Stem cell therapies may help improve symptoms and quality of life for people with epidermolysis bullosa.
June 2021 in “Experimental and Therapeutic Medicine” MEF/KSF-conditioned medium effectively grows mouse hair follicle stem cells with bone-forming potential.
191 citations
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September 2011 in “Cell stem cell” Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
87 citations
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June 2010 in “Stem Cell Research & Therapy” Stem cells can move to brain injury sites and be tracked, showing promise for treating brain diseases.
31 citations
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August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
24 citations
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November 2013 in “Molecular Medicine Reports” Human hair follicle stem cells can become endothelial cells with certain growth factors, useful for vascular treatments.
23 citations
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May 2019 in “Stem cell research & therapy” iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
16 citations
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July 2008 in “BMC Genomics” Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
11 citations
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February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
8 citations
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February 2021 in “Journal of Clinical Medicine” Hair follicle stem cells are promising for blood vessel formation and tissue repair.
4 citations
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January 2014 in “Stem Cell Discovery” Stem cells can be reprogrammed for various treatments, but safety and expansion challenges remain.
3 citations
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May 2022 in “Experimental Dermatology” Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.
1 citations
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February 2023 in “ACS Biomaterials Science & Engineering” The new microwell device helps grow more hair stem cells that can regenerate hair.
December 2024 in “Здобутки клінічної і експериментальної медицини” Advancements in skin regeneration focus on stem cells, nanotechnology, and bioengineered skin to improve healing and reduce scarring.
23 citations
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July 2020 in “Aging Cell” Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
4 citations
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January 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.
4 citations
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June 2021 in “Frontiers in Pharmacology” Bone marrow stem cells and their medium help hair regrowth.
550 citations
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December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
479 citations
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January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
28 citations
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October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
7 citations
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November 2016 in “Oncotarget” UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
4 citations
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January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
1 citations
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September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids from stem cells can help study and treat skin issues but face some challenges.
December 2025 in “International Journal of Pharmacology” iPSC-derived artificial platelets show promise for consistent and effective regenerative therapies.
June 2025 in “Cell Regeneration” Lack of a certain enzyme causes hair to grey early by damaging stem cells, but an antioxidant can help prevent this.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.