10 citations
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June 2009 in “Acta Biochimica Polonica” Old C57BL/6 mice with unsynchronized hair cycles show less melanin in their spleens.
2 citations
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March 2020 in “Skin” Using cidofovir cream for a rare skin disease can cause skin darkening.
SLC24A5 shows a clear selective sweep, but no link to UV radiation intensity.
14 citations
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November 2009 in “Clinical and experimental dermatology” Topical prostaglandin E2 can help treat both alopecia areata and vitiligo.
March 2011 in “Pigment Cell & Melanoma Research” The Agouti gene influences pigmentation and may have a developmental role in deer mice.
13 citations
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April 1982 in “The Journal of Dermatology” Poly(ADP-ribose) synthesis is linked to skin cell differentiation.
January 2023 in “Our Dermatology Online” Most pregnant women experience skin changes, especially increased pigmentation.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
January 2022 in “Skin appendage disorders” Trichoscopy effectively visualizes scalp micropigmentation without invasive methods.
77 citations
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August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which are reversible with treatment.
June 2025 in “Albus Scientia” MC1R gene variations affect skin, hair color, UV sensitivity, and melanoma risk.
4 citations
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November 2024 in “Current Opinion in Genetics & Development” PMEE may help reverse greying hair by boosting melanin production.
8 citations
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January 2019 in “Journal of cosmetic dermatology” Modified phenol peels effectively reduced stubborn skin pigmentation in patients with Lichen Planus Pigmentosus.
5 citations
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May 1958 in “Archives of Dermatology” Treatment with corticosteroids and zinc injections can help hair regrowth and restore pigmentation in alopecia totalis.
23 citations
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May 2017 in “Journal of the American Academy of Dermatology” FFA patients have fewer melanocytes and thinner skin compared to others.
5 citations
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January 2015 in “Skin appendage disorders” Colored hair-thickening fibers can help hide hair loss in some people with Epidermolysis Bullosa but may cause scalp irritation.
152 citations
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December 2003 in “Micron” As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
November 2025 in “Journal of Investigative Dermatology” Light skin shows more inflammation from sun exposure than dark skin.
January 2026 in “Indian Journal of Paediatric Dermatology” A 14-year-old boy has a skin condition called nevus comedonicus, treated with tretinoin cream.
September 2018 in “Obsgyne Review Journal of Obstetric and Gynecology of Siddharth Health Research and Social Welfare Society” Pregnant women often experience a variety of skin problems, including pigmentation changes and stretch marks.
20 citations
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January 2015 in “Current problems in dermatology” Graying hair happens due to aging and might be delayed by new treatments.
12 citations
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April 1990 in “PubMed” Pregnancy can cause skin changes like pigmentation, stretch marks, and temporary hair loss, which often worry the expectant individual.
March 2013 in “Pigment Cell & Melanoma Research” A gene called Taqpep affects cat coat patterns like stripes and blotches.
4 citations
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March 2020 in “JAAD Case Reports” Vitamin B12 deficiency can cause darkening of all nails.
7 citations
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April 2011 in “Expert review of dermatology” The document concludes that patients with skin of color need specialized dermatological care and education to manage unique skin conditions effectively.
July 2002 in “Dermatologic Surgery” Some people's hair turned white or gray after using intense pulsed light for hair removal, and for some, it was permanent.
15 citations
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March 2015 in “Experimental Dermatology” Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.
5 citations
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October 2021 in “Dermatologic Surgery” Platelet-rich plasma (PRP) can significantly improve melasma, a skin pigmentation disorder, but may not add benefits when used with certain other treatments.
Retinoids can help treat skin pigmentation disorders by affecting melanin production.