47 citations
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June 2011 in “Movement Disorders” The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
45 citations
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January 2020 in “International Journal of Molecular Sciences” Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
43 citations
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August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
39 citations
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May 2011 in “Movement Disorders” Finasteride may help reduce symptoms in male Tourette syndrome patients.
39 citations
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March 2009 in “Clinics in plastic surgery” Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.
33 citations
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September 2012 in “Wound Repair and Regeneration” Applying calreticulin can speed up wound healing in diabetics.
32 citations
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May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
32 citations
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November 2004 in “Journal of pharmaceutical sciences” Different tea tree oil mixtures absorb into hair follicles at varying levels, with microemulsion being the most effective.
30 citations
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August 2021 in “Oncogene” miR-22 helps skin cancer grow and spread by activating specific cell signals.
28 citations
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January 2008 in “Journal of medical investigation” Sp6 promotes tooth development by reducing follistatin levels.
26 citations
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February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
25 citations
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January 2021 in “Journal of drugs in dermatology” Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.
23 citations
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June 2015 in “Oncology Letters” Adipose-derived stem cell-conditioned medium can reduce melanoma cell growth and spread.
22 citations
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November 2011 in “Journal of Analytical Toxicology” Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
19 citations
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January 2009 in “International review of cell and molecular biology” Hair's strength and flexibility come from its protein structure and molecular interactions.
18 citations
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February 2025 in “Drug Delivery and Translational Research” The microneedle patches effectively treat allergic conjunctivitis with controlled, sustained release of medication.
18 citations
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March 2014 in “Current Pharmaceutical Biotechnology” Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
17 citations
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May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.
16 citations
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December 2018 in “Plant Science” Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.
16 citations
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February 2018 in “BMC Genomics” Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
15 citations
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July 2004 in “Journal of morphology” Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
14 citations
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February 2018 in “Psychoneuroendocrinology” Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
10 citations
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February 2017 in “Hormone Molecular Biology and Clinical Investigation” Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.
7 citations
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September 2024 in “Applied Microbiology and Biotechnology” Malassezia furfur lipids improve skin health at pH 6.
7 citations
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June 2021 in “Cell Proliferation” Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
6 citations
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October 2016 Understanding how keratin structures in hair are arranged and interact is key for creating methods to extract and purify them.
6 citations
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May 2006 in “Skinmed” Androgens contribute to common male hair loss; more research needed for hair growth medication.
5 citations
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March 2012 in “Microscopy Research and Technique” UVB radiation changes the chemical makeup and dries out human hair but doesn't alter its appearance or texture.
5 citations
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May 2011 in “Movement Disorders” Finasteride may help reduce tic severity in male Tourette syndrome patients.
5 citations
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July 2006 in “Contact dermatitis” Ammonium bisulfite in hair bleach can cause facial eczema.