16 citations
,
July 2006 in “International Journal of Oral and Maxillofacial Surgery” The triple rotation scalp flap technique successfully reconstructed a man's scalp with natural-looking hair growth and minimal scarring.
September 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” CCCA and lichen planopilaris have similar histological features, making them hard to distinguish.
19 citations
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July 2022 in “PNAS Nexus” Similar treatments might work for different types of scarring hair loss.
28 citations
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June 2007 in “Journal of Cutaneous Pathology” IRS premature desquamation is not unique to CCCA and occurs in various scarring alopecias.
July 2025 in “Cell & Bioscience” Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
July 2023 in “IntechOpen eBooks” Some types of hair loss can be reversed, others are permanent, and treatments vary by type.
July 2022 in “JEADV Clinical Practice” The document concludes that different types of permanent hair loss conditions are related and early treatment is key to preventing further damage.
January 2004 in “Linchuang pifuke zazhi” A man lost hair permanently from a salon burn, and surgery was needed to fix the scar.
5 citations
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June 2019 in “British Journal of Dermatology” Chemical hair straightening may be linked to a type of permanent hair loss.
November 2024 in “Journal of Investigative Dermatology” Genetic changes in specific proteins contribute to hair loss in some women of African descent.
25 citations
,
September 2010 in “Journal of Cutaneous Medicine and Surgery” The study found that Central Centrifugal Cicatricial Alopecia mainly affects middle-aged African descent women, is linked to certain hair care practices and genetics, and often goes undiagnosed for years.
2 citations
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June 1980 in “International Journal of Dermatology” Scalp biopsies are important for diagnosing hair loss conditions.
August 2025 in “EMC - AKOS - Trattato di Medicina” Non-scarring alopecia can regrow hair, but scarring alopecia is often permanent and needs quick treatment.
9 citations
,
July 2020 in “JAMA dermatology” Dermatoscopy can help diagnose CCCA without visible hair loss, offering a less invasive option than biopsy.
1 citations
,
February 2023 in “American Journal of Dermatopathology”
June 2023 in “Dermatology reports” The link between pemphigus and the patient's scarring hair loss is still unclear.
September 2023 in “International journal of women’s dermatology” Certain hairstyles, diabetes, scalp infections, and vitamin D deficiency may increase the risk of hair loss in Black women; more research is needed for better treatment.
August 2023 in “Journal of The American Academy of Dermatology” Early treatment is key for permanent hair loss disorders, with options ranging from medications and phototherapy to immunomodulators and antibiotics, depending on severity and type.
15 citations
,
November 2012 in “International Journal of Dermatology” The conclusion is that hair loss from CCCA may be genetic and not solely caused by hair grooming practices.
37 citations
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April 1977 in “Journal of Cutaneous Pathology” Skin biopsy can help diagnose hair loss from trichotillomania.
September 2021 in “CRC Press eBooks” Traumatic alopecia causes hair loss from pulling or rubbing, leading to broken hairs and changes in the scalp.
1 citations
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April 2019 in “Journal of Investigative Dermatology” Oral minoxidil can potentially increase hair growth in people suffering from Central Centrifugal Cicatricial Alopecia.
January 2024 in “Skin Appendage Disorders” Serial Excision Technique improves appearance and quality of life for cicatricial alopecia patients.
3 citations
,
April 2018 in “Journal of Investigative Dermatology” CCCA may be a fibroproliferative disorder, and anti-fibrotic therapies could help.
25 citations
,
September 2014 in “Dermatologic Surgery” Hair transplants can effectively treat hair loss from CCCA in African American women if there's no inflammation.
Mutations in the PADI3 gene may cause central centrifugal cicatricial alopecia in women of African ancestry.
3 citations
,
March 2015 in “Journal of the European Academy of Dermatology and Venereology” Some people with primary cicatricial alopecia also have inflammatory bowel disease, suggesting a possible connection.
July 2023 in “International journal of trichology” Injectable platelet-rich fibrin may stop hair loss from Discoid lupus erythematosus.
15 citations
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March 2015 in “Australasian Journal of Dermatology” Seborrhoeic dermatitis may cause a condition called "seborrhoeic folliculitis," leading to chronic scalp inflammation and scarring hair loss.
January 2011 in “International Journal of Trichology” The document concludes that doctors should recognize congenital triangular alopecia to avoid unnecessary treatments, as it does not respond to steroids like alopecia areata does.