research Efficacy and safety of Finasteride (5 alpha-reductase inhibitor) monotherapy in patients with benign prostatic hyperplasia: A critical review of the literature
Finasteride helps with prostate symptoms but may cause sexual side effects.
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570-600 / 1000+ resultsresearch Differential expression of steroid 5α-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer
SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.
research Medikamentöse Therapie der BPH Ist eine Kombinationstherapie mit 5α-Reduktasehemmern und α-Rezeptorenblockern sinnvoll?
Combination therapy is more effective for prostate volumes over 60 ml.
research Tamsulosin versus finasteride: effect on bother and urinary flow
Tamsulosin works faster, but both drugs have similar effects after 6 months.
research 2008 Best of the Rest in Urological Survey
research An observational study of the association between androgenetic alopecia and size of the prostate
The conclusion is that more hair loss (androgenetic alopecia) is linked to larger prostate size, suggesting hair loss could be an early sign of benign prostatic hyperplasia.
research Gleason grading controversies: what the chemoprevention trials have taught us
Finasteride reduces prostate cancer risk by 30% without affecting Gleason scores.
research Androgen-induced norepinephrine release in male accessory sex organ smooth muscle growth and differentiation
Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.
research Relationship of Serum Prostate Specific Antigen with Hirsutism in Women Having Polycystic Ovary Syndrome Belonging to the Province of Khyber Pakhtunkhwa, Pakistan
Higher PSA levels are linked to more hirsutism in women with PCOS.
research V07-10 SEMINAL VESICULOSCOPY FOR DIAGNOSIS AND MANAGEMENT OF HEMATOSPERMIA
The procedure involving seminal vesiculoscopy, TURED, and balloon dilation effectively treated a man's hematospermia and improved his dysorgasmia.
research [Transurethral seminal vesiculoscopy combined with finasteride for recurrent hematospermia].
Combining TUSV with finasteride effectively treats recurrent hemospermia.
research Dihydrotestosteron und die Rolle der 5α-Reduktasehemmer bei der benignen Prostatahyperplasie
A stronger dual 5α-reductase inhibitor could improve treatment for benign prostatic hyperplasia by further reducing DHT levels.
research Docking and Molecular Dynamics Identify Leads against 5 Alpha Reductase 2 for Benign Prostate Hyperplasia Treatment
New compounds show promise for treating benign prostate hyperplasia with fewer side effects.
research A Chance Finding of High Grade Prostate Cancer in a 35-Year-Old Male – A Case Report and Outcomes of Robotic Radical Prostatectomy in Young Men with Prostate Cancer
A young man with high-grade prostate cancer had successful surgery and good recovery, highlighting the need for awareness in younger men.
research Slow progress in prostate cancer
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
research Pre-receptor regulation of the androgen receptor
Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
research Intracavernous injection of platelet‐rich plasma reverses erectile dysfunction of chronic cavernous nerve degeneration through reduction of prostate hyperplasia evidence from an aging‐induced erectile dysfunction rat model
Platelet-rich plasma can improve erectile function in older individuals by reducing prostate enlargement.
research Assessing dutasteride-associated sexual dysfunction using the U.S. Food and Drug Administration Adverse Event Reporting System
Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.
research Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia
Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
research Análise dos níveis de metilação e de polimorfismos genéticos dos genes GSTP1, MGMT, VDR e AR em pacientes com câncer de próstata
Certain gene combinations may affect prostate cancer risk, and GSTP1 methylation is linked to tumor aggressiveness.
research Prostate cancer update: 2007
2007 research improved understanding of prostate cancer risk, diagnosis, and treatment, but also showed the need for personalized treatment and further study on certain therapies' risks.
research Tamsulosin and Solifenacin : A Dynamic Duo in BPH Management
Tamsulosin and solifenacin together effectively reduce symptoms in BPH patients.
research Focus sulla finasteride: efficacia, meccanismi e raccomandazioni per l'uso clinico
Finasteride effectively treats benign prostatic hyperplasia by reducing prostate size and improving urinary symptoms.
research Rapid and Sensitive LC–MS–MS Method for the Simultaneous Estimation of Alfuzosin and Dutasteride in Human Plasma
A fast and accurate method was developed to measure alfuzosin and dutasteride in human plasma.
research Morphological Changes of Meibomian Glands in Men With Benign Prostate Hyperplasia
Men with benign prostate hyperplasia have more meibomian gland loss and tear film problems.
research Cutaneous melanoma, prostate-specific antigen testing and the subsequent risk of prostate cancer diagnosis: a prospective analysis of the 45 and Up Study
Men with melanoma have a higher risk of later being diagnosed with prostate cancer.
research Sexual adverse events-related to dutasteride e finasteride: analysis of real-life data from Eudra-Vigilance database
research BPH: epidemiology and comorbidities.
BPH is common in older men and often occurs with other age-related health issues.