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research 5-alpha reductase inhibitors use in prostatic disease and beyond
5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
research Effects of androgen on extracellular vesicles from endothelial cells in rat penile corpus cavernosum
Low androgen levels reduce nitric oxide production in rat penile cells.
research Persistent erectile dysfunction in men exposed to the 5α-reductase inhibitors, finasteride, or dutasteride
Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
research Association of Androgenetic Alopecia with Benign Prostatic Hyperplasia: A Case Control Study
Hair loss linked to prostate enlargement; stress and family history important factors.
research Management of Advanced Prostate Cancer Undergoing Major Shift
New treatments are making advanced prostate cancer management more complex but also more hopeful.
research Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry
A new method accurately measures nine specific hormones in human blood.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.
research Finasteride Inhibits Human Prostate Cancer Cell Invasion through MMP2 and MMP9 Downregulation
Finasteride may reduce prostate cancer spread by lowering certain enzyme levels.
research Finasteride plus doxazosin combination tops in BPH
research The Association of Male Pattern Baldness in Men with Benign Prostatic Hyperplasia
Men with male pattern baldness are more likely to have benign prostatic hyperplasia.
research Impact of dutasteride on spermatogenesis and oxidative status in rats.
Dutasteride did not change rat spermatogenesis or oxidative stress but needs more research.
research Assessing finasteride-associated sexual dysfunction using the FAERS database
Finasteride and dutasteride increase sexual dysfunction reports.
research DYS459, DYS391, DYS388 and DYS19 genetic loci have high allelic frequency in patients with prostate cancer
Certain genetic markers may increase or decrease prostate cancer risk.
research Is semen analysis necessary prior to initiation of finasteride treatment?
research Postoperative Urinary Retention is an Independent Predictor of Short-Term and Long-Term Future Bladder Outlet Procedure in Men
Older men with postoperative urinary retention are more likely to need future bladder procedures.
research Androgen Deprivation Therapy in Prostate Cancer: Focusing on Sexual Side Effects
Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.
research Preparation of3H-labelled testosterone metabolites
The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
research Finasteride with Doxazosin to Reduce BPH Progression
research Optimization of LC method for the determination of testosterone and epitestosterone in urine samples in view of biomedical studies and anti-doping research studies
Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.
research A Prospective, 1-Year Trial Using Saw Palmetto Versus Finasteride in the Treatment of Category III Prostatitis/Chronic Pelvic Pain Syndrome
Finasteride improves chronic pelvic pain, saw palmetto doesn't.
research Why would men use finasteride in 2005?
In 2005, men used finasteride mainly to treat an enlarged prostate.
research The Effects of Transdermal Dihydrotestosterone in the Aging Male: A Prospective, Randomized, Double Blind Study
Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
research Оптимизация подходов консервативной терапии доброкачественной гиперплазии предстательной железы ингибиторами 5-альфаредуктазы. Клинико-морфологическое исследование
5-alpha-reductase inhibitors can effectively treat benign prostatic hyperplasia.
research Invalidation of a commercially available human 5α-dihydrotestosterone immunoassay
The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
research Pharmacological Role and Clinical Applications of 5α-Reductase Inhibitors-Review Article for Pharmacists and Healthcare Professionals
5α-reductase inhibitors effectively treat enlarged prostate and hair loss but require careful use due to possible side effects.
research Finasteride en el año 2006
Finasteride lowers prostate cancer risk but may increase high-grade tumors and sexual side effects.
research Inhibitory Effects of Serenoa repens on the Kinetic of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
research Pertinence d’une chimioprévention à partir de l’étude PCPT
Finasteride shows promise for preventing prostate cancer, but more research is needed.