46 citations
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December 2007 in “International Journal of Cardiology” People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.
46 citations
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December 2003 in “Advances in neonatal care” Assessing newborn scalp hair can reveal important health information.
46 citations
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March 2001 in “Journal of endocrinological investigation” 5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
45 citations
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February 2019 in “Journal of Affective Disorders” Melatonin improved mental health and metabolism in women with PCOS.
45 citations
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February 2001 in “Joint bone spine” Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
44 citations
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August 1996 in “Drugs & Aging” Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
43 citations
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August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
43 citations
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January 2007 in “American Journal of Clinical Dermatology” Combined minoxidil and tretinoin solution works as well as regular minoxidil for male hair loss.
43 citations
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May 1986 in “Clinics in Endocrinology and Metabolism” Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
43 citations
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January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
42 citations
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February 1985 in “Journal of the American Academy of Dermatology” Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
42 citations
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January 2007 in “Pediatric dermatology” Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.
42 citations
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January 1998 in “BioDrugs” Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
40 citations
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August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
40 citations
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April 2018 in “Endocrine” PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
40 citations
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December 2016 in “Journal of Dermatological Treatment” JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.
40 citations
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January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.
39 citations
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April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
39 citations
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September 2016 in “Expert Opinion on Drug Delivery” New drug delivery methods can make natural compounds more effective and stable.
39 citations
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September 2013 in “Journal of Cosmetic Dermatology” Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
39 citations
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October 1967 in “British Journal of Dermatology” Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.
38 citations
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March 2017 in “Expert Opinion on Investigational Drugs” Bimatoprost is promising for treating some types of hair loss but needs more testing for androgenetic alopecia.
38 citations
,
June 2015 in “Expert Opinion on Therapeutic Targets” Blocking the prolactin receptor might help treat various diseases, but more research is needed.
38 citations
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June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
38 citations
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June 2004 in “Human Reproduction” The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
38 citations
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February 2023 in “International Journal of Advanced Research in Science Communication and Technology” Plant compounds may offer a promising alternative for cancer treatment.
37 citations
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September 2008 in “The American journal of surgical pathology” Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."
37 citations
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October 2004 in “Adolescent Medicine Clinics” Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.
37 citations
,
November 1995 in “Journal of Investigative Dermatology” Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
36 citations
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June 2019 in “eLife” The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.