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690-720 / 1000+ resultsresearch Influence of Clinical and Sociodemographic Factors on the Management, Costs, and Outcomes of Acute Urinary Retention in the Acute Care Setting
Early intervention for acute urinary retention can reduce costs and improve care.
research The enzyme and inhibitors of 4-ene-3-oxosteroid 5α-oxidoreductase
Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.
research Benign prostatic hyperplasia and male lower urinary symptoms: A guide for family physicians
Family doctors can manage older men with urinary symptoms using exams, tests, and medications.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Catamenial-like seizure exacerbation in mice with targeted ablation of extrasynaptic δGABA-a receptors in the brain
Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.
research 5α-reductase isoenzymes mediate stress-exacerbated Tourette-like responses in animal models
Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.
research CAN PATIENTS WITH LUTS AND BPH DISCERN CHANGES IN PEAK URINARY FLOW RATE AND DO SUCH CHANGES CONTRIBUTE TO OVERALL SATISFACTION WITH TREATMENT?
Finasteride improves urinary symptoms and quality of life in BPH patients, especially with larger prostate size.
research The Acute Anticonvulsant Effects of Deoxycorticosterone in Developing Rats: Role of Metabolites and Mineralocorticoid‐receptor Responses
Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.
research Urinary Retention in Patients with BPH Treated with Finasteride or Placebo over 4 Years
Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.
research Underactive bladder - an underestimated entity
Underactive bladder is hard to diagnose and treat, needing more research.
research Neurosteroids Involved in Regulating Inhibition in the Inferior Colliculus
Neurosteroids help balance brain signals when certain inhibitions are reduced.
research Androgen-induced norepinephrine release in male accessory sex organ smooth muscle growth and differentiation
Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.
research Aqueous extract of Asiasari radix inhibits formalin-induced hyperalgesia via NMDA receptors
Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.
research 332 Recognizing and Treating Undiagnosed Erectile Dysfunction (ED) in Patients Presenting With Lower Urinary Tract Symptoms (LUTS)
Many patients with lower urinary tract symptoms also have undiagnosed erectile dysfunction, which improves with treatment.
research Saw palmetto and finasteride in the treatment of category-iii prostatitis/chronic pelvic pain syndrome
Saw palmetto helps with nighttime urination and urine flow, similar to finasteride.
research Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, InVitro, and In Silico Studies
Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.
research Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors
The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.
research Comparative Study of Therapeutic Effect of Dibenyline, Finasteride, and Combination Drugs for Symptomatic Benign Prostatic Hyperplasia
All treatments helped with prostate symptoms, but the combination of dibenyline and finasteride worked best without extra side effects.
research The use of a retinoid receptor antagonist in a new model to study vitamin A-dependent developmental events.
The retinoid receptor antagonist effectively disrupts vitamin A-related development in embryos.
research Benign Prostatic Hyperplasia and Sexual Dysfunction: Review of the Impact of New Medical and Surgical Therapies on Sexual Health
New BPH treatments have low sexual dysfunction risk but may not improve urinary symptoms as much as traditional surgery.
research Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5α-reductase isoform II inhibition using a cell-free in vitro test system
The saw palmetto extract effectively inhibits an enzyme linked to prostate issues, showing promise for prostate health.
research (PNM-35) Recurrent priapism in a sickle cell disease patient treated with gonadotropin-releasing hormone (GnRH) agonists drugs: a case report
GnRH agonists can help manage recurrent priapism in sickle cell patients, but long-term safety is unclear.
research Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell
Certain drugs change freshwater snail shells to a "banana" shape.
research Clinical research on preoperative application of finasteride in reducing transurethral resection syndrome
Preoperative finasteride can help prevent and reduce transurethral resection syndrome.
research VIBRATIONAL SPECTROSCOPIC INVESTIGATION AND MOLECULAR STRUCTURE OF A 5α-REDUCTASE INHIBITOR: FINASTERIDE
Finasteride's molecular properties and active sites were identified using computational methods.
research Corticotropin releasing factor-1 receptor antagonism associated with favorable outcomes of male reproductive health biochemical parameters
Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
research Use of Minoxidil Sulfate versus Minoxidil Base in Androgenetic Alopecia Treatment: Friend or Foe?
Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.
research Atypical post-finasteride syndrome: A pharmacological riddle
Finasteride and dutasteride can cause severe, lasting side effects.
research Novel Anti-Prostate Cancer Curcumin Analogues That Enhance Androgen Receptor Degradation Activity
New curcumin analogues help fight prostate cancer by breaking down androgen receptors.