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Mercury can disrupt sex hormones and cause reproductive issues.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

A woman with Kallman's syndrome also developed alopecia universalis, a condition not previously linked to Kallman's.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

Evening primrose oil significantly improves hormone levels and reduces BMI and cholesterol in women with PCOS.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Uterine transplants for transgender women are feasible but need more research.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

EZH2 is crucial for uterine gland development and female fertility.