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research Trajectory of hiPSCs derived neural progenitor cells differentiation into dermal papilla-like cells and their characteristics
Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.
research Application of genetically modified umbilical cord blood cells and direct gene therapy for treatment of skin wounds in rats
Genetically modified umbilical cord blood cells improved skin wound healing in rats.
research Immunohistochemical and autoradiographic findings suggest that minoxidil is not localized in specific cells of vibrissa, pelage, or scalp follicles
Minoxidil does not specifically target any hair follicle cells.
research Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells
research Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma
research Exosomes facilitate mRNA and siRNA delivery using cationic liposomes 2X3-DOPE to rat heart mesenchymal cells <i>in vitro</i>
Modified liposomes with exosomes effectively deliver RNA to stem cells.
research 840 Early and late matrix progenitors form the terminally differentiated cell layers of the hair follicle
Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
research Author response: Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration
SMAD4 is crucial for muscle repair in young adults but not in aged mice.
research 881 Ionizing radiation triggers dedifferentiation of outer root sheath cells into stem cell-like progenitors for hair follicle regeneration
research Folliculotropic mycosis fungoides with central nervous system involvement: Demonstration of tumor clonality in intrafollicular T cells using laser capture microdissection
Folliculotropic mycosis fungoides can affect the central nervous system in advanced stages.
research Adalimumab-related alopecia in a patient affected by psoriasis
Adalimumab can cause hair loss and scalp issues in some psoriasis patients.
research Hormone-induced aberrations in electromagnetic adhesion signaling as a developmental factor of androgenetic alopecia
Hormones cause hair loss by affecting cell growth and weakening cell attraction.
research Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation
Human skin xenografting could improve our understanding of skin development, renewal, and healing.
research 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment
SM04755 may be an effective topical treatment for psoriasis.
research In-Situ Tensile Testing of Hair Fibers in An Environmental Scanning Electron Microscope (ESEM)
Hair fibers break by cuticle cell slipping, shape changing, cuticle fraying, and surface cracking when stretched under specific conditions.
research Modern strategies for the prevention and treatment of post-burn scars (a systematic review)
Combining surgical and nonsurgical methods is key to reducing post-burn scars.
research CLINICAL INSIGHTS FOR HAIR RESTORATION: A CASE STUDY ON UC-MSCs DERIVED SECRETOME THERAPY IN ALOPECIA
UC-MSCs derived secretome therapy may help treat hair loss safely.
research 877 Loss of UBE2N in keratinocytes leads to skin inflammation and immune infiltration through IRAK1/4-mediated processes
Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.
research 586 Interest of Silybum marianum extract, Manganese PCA and Lespedeza capitata extract in a new anti-hair loss serum to stimulate hair growth and prolong anagen phase
The extract of Silybum marianum, Manganese PCA, and Lespedeza capitata can boost hair growth and extend the growth phase when combined in a serum.
research LB1011 Oncogenic ras mutation induces spatiotemporally specific tissue deformation through converting fluctuated into sustained ERK activation
A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.
research Mono‐letter mnemonics in dermatology
Mnemonics with one letter are useful and easy to remember for learning dermatology.
research MORPHOLOGICAL CHARACTERISTICS OF EPIDERMIS AND DERMIS IN PATIENTS WITH DIFFUSE ALOPECIA, ANDROGENETIC ALOPECIA AND ALOPECIA AREATA
All types of alopecia involve hair follicle damage, especially in alopecia areata.
research EFFECTIVENESS OF PLASMOTHERAPY IN VARIOUS NOSOLOGIES
PRP therapy is effective and safe for treating various diseases.
research 265 Modulation of disease-central cytokine pathways with TAK-279, a highly selective oral tyrosine kinase 2 (TYK2) inhibitor, defines clinical response in patients with psoriasis
TAK-279 effectively reduces psoriasis symptoms and is safe.
research Minoxidil-induced ophthalmic hypertension (case report)
Stopping minoxidil and using prostaglandin analogues improved the man's eye condition.
research 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes
SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.
research Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
Hydrogel scaffolds can help wounds heal better and grow hair.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.