20 citations
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December 2011 in “Journal of inherited metabolic disease” Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.
84 citations
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December 2018 in “Genetics in Medicine” Pegvaliase is recommended for treating adults with phenylketonuria.
2 citations
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November 1978 in “JAMA” Valproic acid is an effective seizure medication with some temporary side effects.
14 citations
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May 2023 in “Dermatologic Surgery” VYC-12L effectively improves skin smoothness, reduces fine lines, and boosts hydration.
294 citations
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February 1994 in “PubMed” Valproic acid is an effective and safe first-choice treatment for many types of seizures.
2 citations
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April 2023 in “Curēus” Valproic acid can cause muscle damage and liver issues, which improve after stopping the drug.
24 citations
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November 1978 in “JAMA” Valproic acid is effective for various seizures, but may cause temporary side effects like drowsiness and stomach issues.
8 citations
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October 2019 in “The Journal of surgical research/Journal of surgical research” Sodium valproate helps skin healing by affecting GABA and histone deacetylase.
82 citations
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January 2011 in “New Phytologist” VILLIN4 helps root hair growth by organizing actin with calcium.
June 2023 in “International Journal of Pharmaceuticals Nutraceuticals and Cosmetic Science” New information shows Valproate may protect the brain and reduce breathing failure risk but can cause liver damage and other side effects, with genetics affecting dosage needs.
August 2018 in “Online journal of neurology and brain disorders” Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.
73 citations
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January 1980 in “Annals of Neurology” Valproic acid can cause serious side effects, including pancreatitis and even death.
50 citations
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September 2009 in “Molecular Genetics and Metabolism” A new gene mutation causes vitamin D resistance and rickets, treatable with calcium therapy.
4 citations
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October 2023 in “African Journal of Urology” Older parental age, rural living, and specific genetic mutations increase hypospadias risk in children.
August 2025 in “Frontiers in Nutrition” Leucine levels may affect hair loss after bariatric surgery.
February 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Rodent spiny hair traits are due to genetic factors other than the Edar gene.
2 citations
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September 2015 in “Türk pediatri arşivi : İstanbul çocuk kliniği dergisi” Valproic acid can very rarely cause nail separation, which usually gets better on its own after stopping the drug.
June 2021 in “Clinical neuropsychopharmacology and therapeutics” Valproic acid can cause hair color change in older men.
September 2018 in “Practical diabetes” Sodium valproate is not recommended as a first-line treatment for neuropathy but may be used in resistant cases.
12 citations
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May 2005 in “Journal of the American Geriatrics Society” Stopping valproate and using lactulose can quickly treat valproate-induced hyperammonemia.
January 2025 in “International Journal of Pharmacology” Both steroids, especially cyproterone acetate, harm quail's vital organs.
4 citations
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October 2015 in “JAAD Case Reports” Surgical grafting may fix nail issues caused by valproic acid.
December 2021 in “Black sea journal of health science” Valproic acid can cause a rare allergic reaction leading to fluid around the lungs and heart, which is treatable by changing medication.
February 2024 in “Plant Cell Reports” AtVPS29 is essential for proper plant growth by regulating gibberellin signaling.
1 citations
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April 2023 in “Heliyon” Disitamab vedotin and gemcitabine effectively treated bladder cancer without major side effects.
5 citations
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January 2015 in “Molecular Genetics and Metabolism” 1 citations
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April 2002 in “PubMed” Anti-epileptic drugs may cause visual and hair side effects due to enzyme inhibition, especially in genetically predisposed individuals.
January 2024 in “Specialty journal of Pharmacognosy Phytochemistry and Biotechnology” Genetic factors may influence how well valproic acid works and its side effects in epilepsy treatment.
January 2006 in “OpenCommons at University of Connecticut (University of Connecticut)” Overexpressing AVP1 and AtNHX1 in plants improves salt tolerance and root hair development.
April 2025 in “Suez Canal University Medical Journal” Valproic acid can rarely cause fluid buildup around the lungs and heart.