1 citations
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December 2015 in “Endocrinology” Decanoic acid may help treat PCOS by reducing androgen levels and improving glucose sensitivity.
1 citations
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September 2007 in “Neuromuscular disorders” The treatment with valproate, acetylcarnitine, folic acid, and vitamin B12 may improve muscle strength in children with SMA without significant side effects.
2 citations
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September 2021 in “Human Psychopharmacology: Clinical and Experimental” Valproate can cause hair problems, but there are ways to manage them.
5 citations
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November 2012 in “Journal of Clinical Psychopharmacology” Valproic acid and isoniazid can interact, causing toxicity, so careful monitoring is needed.
19 citations
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December 1999 in “International Journal of Dermatology” Dihydroxyacetone in self-tanning lotion helped reduce sun-related skin issues in a woman with variegate porphyria.
16 citations
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March 1986 in “Biochemical Pharmacology”
February 2023 in “Indian journal of private psychiatry/Indian Journal of Private Psychiatry” Valproic acid can rarely cause reversible nail discoloration.
2 citations
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November 2011 in “Current psychiatry” 20 citations
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August 1981 in “Developmental Medicine & Child Neurology” 13 citations
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June 1981 in “Developmental Medicine & Child Neurology”
December 2025 in “Scientific Reports” Valproic acid helps hair follicle stem cells survive better in low oxygen and glucose conditions.
12 citations
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May 2005 in “Journal of the American Geriatrics Society” Stopping valproate and using lactulose can quickly treat valproate-induced hyperammonemia.
1 citations
,
July 2020 in “Acta Neuropsychologica” Valproic acid effectively reduces aggressive and impulsive behaviors in brain injury patients with acceptable side effects.
May 2024 in “European Journal of Immunology” Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.
1 citations
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September 2007 in “European journal of paediatric neurology” Low dose valproic acid treatment caused hair loss in a young patient.
4 citations
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December 2024 in “European Journal of Medicinal Chemistry” New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.
6 citations
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June 2013 in “Toxicological Research” Topical Valproate is safe for human skin and unlikely to cause irritation.
17 citations
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January 2008 in “Journal of the American Academy of Dermatology” Valproic acid can cause hair loss, but information on hair color change is not detailed.
2 citations
,
September 2014 in “International Journal of Dermatology” Sodium valproate can worsen psoriasis-like skin conditions.
July 2023 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ” Antiandrogens help improve developmental delays caused by valproic acid in rats.
88 citations
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July 2009 in “Experimental and Clinical Endocrinology & Diabetes” 7 citations
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September 2007 Valproate sustained-release is effective and generally safe for short-term treatment of new partial epilepsy.
4 citations
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October 2015 in “JAAD Case Reports” Surgical grafting may fix nail issues caused by valproic acid.
6 citations
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April 2013 in “International Journal of Dermatology” Valproic acid helped hair growth in alopecia patient; more research needed.
29 citations
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March 1987 in “Therapeutic Drug Monitoring” Combining sodium valproate with other epilepsy drugs increases ammonia levels and side effects.
9 citations
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May 2001 in “Journal of the American Veterinary Medical Association” A cat's hyperactivity and hair loss were caused by eating valproic acid but improved after stopping access to the drug.
January 2004 in “Headache” Divalproex sodium significantly improved headaches in two-thirds of patients.
November 2024 in “Journal of Cosmetic Dermatology” Valproic acid microemulsions improve skin delivery compared to regular solutions.
3 citations
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January 2003 in “Synthetic Communications” Scientists made two new chemicals that might help treat diseases caused by male hormones.
25 citations
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December 2005 in “Molecular Genetics and Metabolism” Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.