38 citations
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May 1971 in “Clinical genetics” A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
31 citations
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January 2001 in “PubMed” Certain medications can negatively impact male fertility.
April 2007 in “The Journal of Urology” Finasteride reduces bleeding risk during prostate surgery.
12 citations
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February 2003 in “European Urology Supplements” Dutasteride reduces DHT more effectively than finasteride.
April 2017 in “Reactions Weekly” Finasteride may cause weak ejaculation and reduced semen volume.
2 citations
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October 1999 in “The Journal of Urology” 
8 citations
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July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
15 citations
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January 2017 in “Advances in Experimental Medicine and Biology” 5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.
August 2016 in “Journal of Investigative Dermatology”