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GlossaryVascular Endothelial Growth Factor

stimulates new blood vessel formation

Vascular Endothelial Growth Factor (VEGF) is a protein that stimulates the formation of new blood vessels. It plays a crucial role in both normal processes like wound healing and the growth of hair, as well as in pathological conditions such as cancer, where it can promote tumor growth by increasing blood supply.

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Comparison Between Single- Versus Double-Spin Prepared Platelet-Rich Plasma Injection in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor

research Comparison between single- versus double-spin prepared platelet-rich plasma injection in treatment of female pattern hair loss: clinical effect and relation to vascular endothelial growth factor

10 citations , September 2020 in “Archives of Dermatological Research”

Both methods improve hair density and thickness; double-spin may be more effective.

The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

research The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

90 citations , January 2003 in “The Journal of Urology”

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

research Ginsenoside Rg3 Up-regulates the Expression of Vascular Endothelial Growth Factor in Human Dermal Papilla Cells and Mouse Hair Follicles

20 citations , December 2013 in “PTR. Phytotherapy research/Phytotherapy research”

Ginsenoside Rg3 may help hair growth by increasing a growth-related protein in hair cells.

17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells

research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells

18 citations , March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Hair Growth Promoting Effect of Dermal Papilla-Like Tissues from Canine Adipose-Derived Mesenchymal Stem Cells Through Vascular Endothelial Growth Factor

research Hair growth promoting effect of dermal papilla like tissues from canine adipose-derived mesenchymal stem cells through vascular endothelial growth factor

8 citations , January 2016 in “Journal of Veterinary Medical Science”

Lab-made tissues from dog fat stem cells can help grow hair by releasing a growth factor.

research Effects of finasteride on expression of vascular endothelial growth factor and microvascular density in retina of early diabetic rats

1 citations , January 2004 in “Chinese Journal of New Drugs and Clinical Remedies”

Finasteride reduces VEGF expression and microvascular growth in diabetic rat retinas.

research Differing responses of human follicular and nonfollicular scalp cells in an in vitro wound healing assay: Effects of estrogen on vascular endothelial growth factor secretion

30 citations , March 2008 in “Wound Repair and Regeneration”

Estrogen affects scalp cell types differently, enhancing some wound healing processes.

research Finasteride Reduces Microvessel Density and Expression of Vascular Endothelial Growth Factor in Renal Tissue of Diabetic Rats

7 citations , March 2015 in “The American Journal of the Medical Sciences”

Finasteride helps reduce blood vessel growth in diabetic rat kidneys.

Extracellular Vesicles From 3D Cultured Dermal Papilla Cells Improve Wound Healing Via Krüppel-Like Factor 4/Vascular Endothelial Growth Factor A-Driven Angiogenesis

research Extracellular vesicles from 3D cultured dermal papilla cells improve wound healing via Krüppel-like factor 4/vascular endothelial growth factor A -driven angiogenesis

1 citations , January 2023 in “Burns and trauma”

Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.

research Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells

192 citations , March 1998 in “British Journal of Dermatology”

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

research Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells

135 citations , January 1996 in “Journal of Investigative Dermatology”

research In vitro effects of baicalin on the growth of human hair follicles and secretion of vascular endothelial growth factor by human dermal papilla cells

1 citations , January 2007 in “Chinese Journal of Dermatology”

Baicalin may help hair growth by increasing VEGF secretion.

research Expression of vascular endothelial growth factor, apoptosis inhibitors (survivin and p16) and CCL27 in alopecia areata before and after diphencyprone treatment: an immunohistochemical study

58 citations , May 2004 in “British Journal of Dermatology”

Diphenylcyclopropenone treatment helps hair growth in alopecia areata by promoting blood vessel growth and cell survival.

research Expression and localization of the vascular endothelial growth factor and changes of microvessel density during hair follicle development of Liaoning cashmere goats

4 citations , January 2013 in “Genetics and Molecular Research”

VEGF and microvessel density are closely linked and peak during specific hair growth phases in cashmere goats.

research Epidermal Vascular Endothelial Growth Factor Production Is Required for Permeability Barrier Homeostasis, Dermal Angiogenesis, and the Development of Epidermal Hyperplasia

100 citations , August 2008 in “American Journal Of Pathology”

VEGF-A is crucial for normal skin function and may be linked to psoriasis.

Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute

research Gelatin-chondroitin-6-sulfate-hyaluronic acid scaffold seeded with vascular endothelial growth factor 165 modified hair follicle stem cells as a three-dimensional skin substitute

45 citations , October 2014 in “Stem cell research & therapy”

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

research Differentiation of human hair follicle stem cells into endothelial cells induced by vascular endothelial and basic fibroblast growth factors

24 citations , November 2013 in “Molecular Medicine Reports”

Human hair follicle stem cells can become endothelial cells with certain growth factors, useful for vascular treatments.

research A Split Scalp Study of Single versus Double Spin Platelet-rich plasma Injections in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor in PRP

1 citations , October 2021 in “QJM: An International Journal of Medicine”

Double-spin PRP is more effective for treating female hair loss than single-spin PRP.

research Activation of cAMP Signaling in Response to α-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells

6 citations , August 2022 in “International journal of molecular sciences”

α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.

Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Microvessel Density

research Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Micro Vessel Density

January 2024

Recombinant human growth hormone helps burn wounds heal faster by increasing blood vessel growth.

Urotensin II Promotes the Proliferation and Secretion of Vascular Endothelial Growth Factor in Rat Dermal Papilla Cells by Activating the Wnt-Beta-Catenin Signaling Pathway

research Urotensin II promotes the proliferation and secretion of vascular endothelial growth factor in rat dermal papilla cells by activating the Wnt-β-catenin signaling pathway

June 2023 in “Italian Journal of Medicine”

Urotensin II increases growth and VEGF production in rat skin cells by turning on the Wnt-β-catenin pathway.

research Change of Vascular Endothelial Growth Factor resulted by different Minoxidil praeparatums in C57BL/6 Mouse

January 2006 in “Chinese Journal of Aesthetic Medicine”

Lipo-minoxidil increases VEGF expression more than regular minoxidil.

research Vascularization of skin substitute constructed by vascular endothelial growth factor 165 gene-modified hair follicle stem cells compounded with three-dimensional gelatin-chondroitin sulfate-hyaluronic acid

June 2014

The modified stem cells with VEGF165 in a special scaffold improved blood vessel growth and wound healing for skin repair.

research Effects of "Huoxue Bushen Mixture" on Vascular Endothelial Growth Factor Expression in Human Dermal Papilla Cell

January 2010 in “Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai”

Huoxue Bushen Mixture boosts VEGF expression and hair growth.

research Effects of latanoprost on vascular endothelial growth factor protein synthesis in human dermal papilla cells

January 2006

Latanoprost increases VEGF protein in human cells, which may help hair growth.

research Topical Rice Bran Oil (Oryza sativa L.) Has The Same Effect With 2% Topical Minoxidil To Prevent Senile Alopecia Through Improved Vascular Endothelial Growth Factor (VEGF) Protein Expression, Hair Follicle Diameter And Length In Wistar Rats (Rattus norvegicus) Exposed To Ultraviolet B Light

January 2023 in “International journal of research publications”

Rice bran oil works as well as 2% minoxidil to prevent hair loss and promote hair growth.