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GlossaryVascular Endothelial Growth Factor

stimulates new blood vessel formation

Vascular Endothelial Growth Factor (VEGF) is a protein that stimulates the formation of new blood vessels. It plays a crucial role in both normal processes like wound healing and the growth of hair, as well as in pathological conditions such as cancer, where it can promote tumor growth by increasing blood supply.

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research Epidermal Vascular Endothelial Growth Factor Production Is Required for Permeability Barrier Homeostasis, Dermal Angiogenesis, and the Development of Epidermal Hyperplasia

100 citations , August 2008 in “American Journal Of Pathology”

VEGF-A is crucial for normal skin function and may be linked to psoriasis.

17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells

research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells

18 citations , March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Extracellular Vesicles From 3D Cultured Dermal Papilla Cells Improve Wound Healing Via Krüppel-Like Factor 4/Vascular Endothelial Growth Factor A-Driven Angiogenesis

research Extracellular vesicles from 3D cultured dermal papilla cells improve wound healing via Krüppel-like factor 4/vascular endothelial growth factor A -driven angiogenesis

1 citations , January 2023 in “Burns and trauma”

Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.

research Activation of cAMP Signaling in Response to α-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells

6 citations , August 2022 in “International journal of molecular sciences”

α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.

research Unexpected Autocrine Role of Vascular Endothelial Growth Factor in Squamous Cell Carcinoma

1 citations , February 2009 in “Journal of Investigative Dermatology”

VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.

research Vascularization of skin substitute constructed by vascular endothelial growth factor 165 gene-modified hair follicle stem cells compounded with three-dimensional gelatin-chondroitin sulfate-hyaluronic acid

June 2014

The modified stem cells with VEGF165 in a special scaffold improved blood vessel growth and wound healing for skin repair.

The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

research The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

90 citations , January 2003 in “The Journal of Urology”

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute

research Gelatin-chondroitin-6-sulfate-hyaluronic acid scaffold seeded with vascular endothelial growth factor 165 modified hair follicle stem cells as a three-dimensional skin substitute

45 citations , October 2014 in “Stem cell research & therapy”

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia

research Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia

11 citations , September 2019 in “Dermatologic Surgery”

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

research Topical tacrolimus suppresses the expression of vascular endothelial growth factor and insulin-like growth factor-1 in late anagen

6 citations , June 2009 in “Clinical and Experimental Dermatology”

Topical tacrolimus reduces certain growth factors in hair follicles.

research Induction of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Expression in Stored Micrografts by Aminoguanidine

3 citations , November 2005 in “Dermatologic Surgery”

Aminoguanidine increases a specific growth signal in stored hair grafts, which may help them survive better after being transplanted.

research A Split Scalp Study of Single versus Double Spin Platelet-rich plasma Injections in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor in PRP

1 citations , October 2021 in “QJM: An International Journal of Medicine”

Double-spin PRP is more effective for treating female hair loss than single-spin PRP.

research Induction of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Expression in Stored Micrografts by Aminoguanidine

1 citations , November 2005 in “Dermatologic Surgery”

Aminoguanidine increases VEGF in stored hair micrografts, potentially improving their viability after transplant.

Analysis of Thymosin β4 and Vascular Endothelial Growth Factor Expression in Normal Human Tissues Using Tissue Microarray

research Analysis of Thymosin β4 and Vascular Endothelial Cell Growth Factor (VEGF) Expression in Normal Human Tissues Using Tissue Microarray

December 2009 in “Saengmyeong gwahag hoeji/Saengmyeong gwahak hoeji”

Thymosin β4 and VEGF are important for blood vessel formation in many organs.

research Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells

135 citations , January 1996 in “Journal of Investigative Dermatology”

research Differing responses of human follicular and nonfollicular scalp cells in an in vitro wound healing assay: Effects of estrogen on vascular endothelial growth factor secretion

30 citations , March 2008 in “Wound Repair and Regeneration”

Estrogen affects scalp cell types differently, enhancing some wound healing processes.

research Use of natural molecules as anti-angiogenic inhibitors for vascular endothelial growth factor receptor

16 citations , December 2012 in “Bioinformation”

Curcumin, EGCG, barringtozenol, and finasteride are effective VEGFR inhibitors.

Hair Growth Promoting Effect of Dermal Papilla-Like Tissues from Canine Adipose-Derived Mesenchymal Stem Cells Through Vascular Endothelial Growth Factor

research Hair growth promoting effect of dermal papilla like tissues from canine adipose-derived mesenchymal stem cells through vascular endothelial growth factor

8 citations , January 2016 in “Journal of Veterinary Medical Science”

Lab-made tissues from dog fat stem cells can help grow hair by releasing a growth factor.

research Loss of Vascular Endothelial Growth Factor in Human Alopecia Hair Follicles

47 citations , May 1995 in “Journal of Investigative Dermatology”

Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.

research Expression of vascular endothelial growth factor, apoptosis inhibitors (survivin and p16) and CCL27 in alopecia areata before and after diphencyprone treatment: an immunohistochemical study

58 citations , May 2004 in “British Journal of Dermatology”

Diphenylcyclopropenone treatment helps hair growth in alopecia areata by promoting blood vessel growth and cell survival.

Cold Shock Therapy Promotes Hair Growth in Association with Upregulation of Cold-Inducible RNA-Binding Protein and Vascular Endothelial Growth Factor

research Cold shock therapy promotes hair growth in association with upregulation of cold-inducible RNA-binding protein and vascular endothelial growth factor

1 citations , August 2024 in “Journal of Dermatological Science”

Cold shock therapy may help hair grow by increasing certain proteins.

Urotensin II Promotes the Proliferation and Secretion of Vascular Endothelial Growth Factor in Rat Dermal Papilla Cells by Activating the Wnt-Beta-Catenin Signaling Pathway

research Urotensin II promotes the proliferation and secretion of vascular endothelial growth factor in rat dermal papilla cells by activating the Wnt-β-catenin signaling pathway

June 2023 in “Italian Journal of Medicine”

Urotensin II increases growth and VEGF production in rat skin cells by turning on the Wnt-β-catenin pathway.

research Topical Rice Bran Oil (Oryza sativa L.) Has The Same Effect With 2% Topical Minoxidil To Prevent Senile Alopecia Through Improved Vascular Endothelial Growth Factor (VEGF) Protein Expression, Hair Follicle Diameter And Length In Wistar Rats (Rattus norvegicus) Exposed To Ultraviolet B Light

January 2023 in “International journal of research publications”

Rice bran oil works as well as 2% minoxidil to prevent hair loss and promote hair growth.

research Role of vascular endothelial growth factor in androgenetic alopecia

July 2023 in “Chinese Journal of Dermatology”

Vascular endothelial growth factor might be involved in common hair loss.

research Effects of Finasteride on Vascular Endothelial Growth Factor

35 citations , January 2002 in “Scandinavian Journal of Urology and Nephrology”

Finasteride reduces prostate bleeding by affecting blood vessel growth.

research Expression of vascular endothelial growth factor (VEGF) in various compartments of the human hair follicle

105 citations , December 1998 in “Archives of Dermatological Research”

Dermal papilla cells mainly drive blood vessel growth in hair follicles.

research Genetic effects of vascular endothelial growth factor and its receptor 2 on feather maturity in three chicken breeds

1 citations , January 2019 in “British Poultry Science”

VEGF and VEGFR-2 genes influence feather maturity, and specific genetic markers can improve chicken breeding.

research Tissue microarray를 이용한 사이모신 베타4(Thymosin β4)와 vascular endothelial cell growth factor (VEGF)의 정상 인간 조직 발현 양상 연구

December 2009 in “생명과학회지”

Thymosin β4 and VEGF are important for organ function and may help with blood vessel formation.

research Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells

192 citations , March 1998 in “British Journal of Dermatology”

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

research [Experimental study on vascular endothelial growth factor 165 gene-modified rat hair follicle stem cells mediated by lentiviral vector].

February 2014 in “PubMed”

Modified rat hair follicle stem cells can help create artificial hair follicles, blood vessels, and skin.