180 citations
,
July 1973 in “The New England Journal of Medicine” Minoxidil effectively lowers blood pressure with few side effects.
127 citations
,
June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
119 citations
,
March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
75 citations
,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
70 citations
,
November 2013 in “The BMJ” Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.
68 citations
,
September 2003 in “British Journal of Dermatology” Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
47 citations
,
July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
45 citations
,
April 2013 in “Cell Transplantation” Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.
43 citations
,
December 2013 in “Stem Cells” Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.
35 citations
,
January 2013 in “The Journal of experimental medicine/The journal of experimental medicine” CD98hc's role in skin health decreases with age.
31 citations
,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
23 citations
,
June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
20 citations
,
August 2018 in “The World Journal of Men's Health” Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
17 citations
,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
14 citations
,
November 2006 in “Current Medicinal Chemistry” New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
14 citations
,
January 2001 in “Primary Care Update for Ob/gyns” Primary care doctors should address female sexual dysfunctions to improve women's sexual health and life quality.
13 citations
,
January 2016 in “Burns & Trauma” Vacuum massage may improve skin elasticity and induce changes in skin cells, but evidence for treating burn scars is insufficient and more research is needed.
13 citations
,
December 2012 in “Frontiers in bioscience” Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
10 citations
,
January 2023 in “Molecular and Cellular Biochemistry” Solanum nigrum shows promise for treating COVID-19 and its complications, but more research is needed.
10 citations
,
December 2015 in “International Journal of Molecular Sciences” PDCD4 is important for controlling skin cell growth and healing.
10 citations
,
November 2014 in “Sexual medicine reviews” Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.
9 citations
,
July 2021 in “Journal of Natural Medicines” Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.
5 citations
,
August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
2 citations
,
May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
2 citations
,
March 2021 in “Carpathian Journal of Food Science and Technology” Caraway, Chinese chives, and cassia may improve health and prevent diseases due to their nutrients and medicinal properties.
1 citations
,
July 2025 in “Frontiers in Endocrinology” ApoBDs, once seen as waste, are now viewed as potential tools for disease treatment and tissue repair.
1 citations
,
February 2022 in “Veterinární Medicína” A cat fully recovered from minoxidil poisoning with specific treatments.
1 citations
,
January 2009 in “Trepo - Institutional Repository of Tampere University” Vitamin D may help regulate cholesterol and influence prostate cancer development.
February 2026 in “BMC Plastic and Reconstructive Surgery” Induced pluripotent stem cells could improve chronic wound healing but face safety and effectiveness challenges.
January 2026 in “Nano-Micro Letters” 4D scaffolds made with melt electrowriting can change shape for use in medicine.