14 citations
,
April 2009 in “Acta Medica Scandinavica” Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.
25 citations
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December 2001 in “Expert Opinion on Pharmacotherapy” Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
180 citations
,
July 1973 in “The New England Journal of Medicine” Minoxidil effectively lowers blood pressure with few side effects.
86 citations
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July 1990 in “British Journal of Pharmacology” Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
11 citations
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January 1980 in “Southern Medical Journal” Minoxidil effectively treats severe hypertension but has notable side effects.
74 citations
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May 2004 in “Journal of Clinical Hypertension” Minoxidil effectively treats severe hypertension, but watch for side effects.
August 2018 in “Dermatologic Surgery”
19 citations
,
May 1979 in “Archives of internal medicine” Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.
119 citations
,
October 1992 in “Fundamental & Clinical Pharmacology” Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
51 citations
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April 1982 in “Lancet” Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.
57 citations
,
February 1975 in “Journal of Clinical Investigation” Minoxidil boosts plasma renin activity, influenced by control plasma renin activity and changes in sympathetic tone.
18 citations
,
July 1975 in “Clinical Pharmacology & Therapeutics” Oral minoxidil effectively controls blood pressure quickly and safely.
1 citations
,
June 2023 in “Frontiers in Pharmacology” Vasodilators may worsen abdominal aortic aneurysm.
28 citations
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August 2013 in “Hypertension” Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.
3 citations
,
March 2012 in “Arab Journal of Urology” Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.
5 citations
,
January 1988 in “Analytical profiles of drug substances” Minoxidil helps lower blood pressure and can also promote hair growth.
1 citations
,
March 2023 in “Journal of the American College of Cardiology”
100 citations
,
March 1973 in “American Journal of Cardiology” Minoxidil effectively lowers blood pressure without major side effects.
17 citations
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May 1975 in “Clinical Pharmacology & Therapeutics”
47 citations
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October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
55 citations
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October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
43 citations
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May 1978 in “JAMA” Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.
2 citations
,
August 2014 in “PubMed” Losartan may help treat Postural Orthostatic Tachycardia Syndrome (POTS) symptoms.
102 citations
,
September 1977 in “The Lancet” Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.
January 1983 in “Side effects of drugs annual” Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.
52 citations
,
March 1979 in “Toxicology and Applied Pharmacology” Minoxidil can cause heart muscle damage in dogs.
90 citations
,
January 1989 in “PubMed” 18 citations
,
February 2024 in “Nutrients” A new pomegranate extract lowers blood pressure and has health benefits.
25 citations
,
December 1974 in “Clinical Pharmacology & Therapeutics” Propranolol affects heart rate and renin levels in minoxidil-treated patients.