Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.
October 2023 in “Apollo medicine” The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
September 2023 in “Clinical, Cosmetic and Investigational Dermatology” Higher SHBG levels are linked to less severe hair loss in women, but vitamin D levels don't seem to affect hair loss.
Different genes cause Female Pattern Hair Loss compared to male hair loss, and treatments vary, but more research is needed to understand it fully.
March 2023 in “International journal of trichology” Six genetic conditions are often linked to complete scalp hair loss in children.
January 2022 in “IntechOpen eBooks” Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.
December 2025 in “Journal of Cell Communication and Signaling” Vitamin D receptor is crucial for hair health and may help treat hair loss.
71 citations
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October 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Vitamin D receptor helps prevent skin cancer and supports skin health.
45 citations
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September 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Vitamin D3 and its receptor help protect skin from UVB-related cancer.
21 citations
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January 2006 in “Hormone Research in Paediatrics” A mutation in the VDR gene affects hair cycling without needing ligand binding.
12 citations
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December 2016 in “The FASEB Journal” Lack of vitamin D receptor causes hair loss in mice by allowing certain genes to overactivate.
7 citations
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June 2016 in “Bone Research” A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.
May 2024 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” Certain gene combinations may affect prostate cancer risk, and GSTP1 methylation is linked to tumor aggressiveness.
January 2011 in “Guangdong Medical Journal” Low Vitamin D receptor levels in hair follicles may contribute to alopecia areata.
June 2010 in “Seoul National University Open Repository (Seoul National University)” Reduced Vitamin D receptor expression may cause hair loss through the Wnt/b-catenin pathway.
October 1990 in “Pediatric Research” Nocturnal calcium infusions improved a boy's severe rickets without causing hair loss.
166 citations
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February 2005 in “Behavioural brain research” Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.
144 citations
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December 2004 in “Molecular Endocrinology” The vitamin D receptor is essential for normal hair growth, even without its usual binding.
137 citations
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April 2001 in “Journal of Clinical Investigation” Alopecia in these mice is caused by defective hair cycle communication due to missing vitamin D receptor function, not vitamin D levels.
119 citations
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October 1998 in “Endocrinology” Diet can prevent bone issues but not hair loss in mice lacking vitamin D receptors.
115 citations
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December 2001 in “Endocrinology” Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.
114 citations
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June 2000 in “Endocrinology” Alopecia in VDR knockout mice is due to a defect in hair cycle initiation, not keratinocyte issues.
111 citations
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April 2006 in “Annals of the New York Academy of Sciences” Vitamin D receptor is essential for healthy bones and skin.
109 citations
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June 2011 in “Molecular and Cellular Endocrinology” Vitamin D receptor mutations can cause alopecia by affecting hair growth genes.
95 citations
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July 2006 in “British Journal of Dermatology” Vitamin D receptors in hair follicles change with the hair cycle, affecting hair growth.
67 citations
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August 2004 in “Endocrinology” A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.
57 citations
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August 1997 in “Pediatrics International” VDDR I and II are genetic disorders affecting vitamin D use, causing rickets, with VDDR I treatable by vitamin D supplements and VDDR II needing high doses and calcium.
56 citations
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September 2014 in “Molecular Endocrinology” Vitamin D receptor is essential for hair growth signaling.
56 citations
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November 2012 in “Endocrinology” Vitamin D receptor is essential for proper skin healing after injury.
54 citations
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January 2007 in “The Journal of Steroid Biochemistry and Molecular Biology” Vitamin D receptor is essential for hair growth and preventing hair loss.