81 citations
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June 2006 in “Experimental Neurology” Neurosteroids may help prevent seizures in epilepsy.
13 citations
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January 2020 in “Neuroscience” Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
17 citations
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January 2013 in “Talanta” A new method was developed to accurately measure enzyme activity related to prostate health.
July 2024 in “Journal of Investigative Dermatology” A KLK5 inhibitor effectively improved skin symptoms in a mouse model of Netherton Syndrome.
59 citations
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January 1976 in “Vitamins and hormones” Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.
3 citations
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October 2021 in “Clinica Chimica Acta” Hormone levels in hair vary across the head, with the highest concentration of a key hormone linked to hair loss at the top.
22 citations
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January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” A new method accurately measures nine specific hormones in human blood.
April 2018 in “The Journal of Urology” Dutasteride use can lead to a stable decline in sexual function that is not affected by age or prostate size.
Suppressing ODC activity reduces tumor growth in hair follicles.
6 citations
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August 2022 in “Molecules” A hair test shows promise for early mood disorder diagnosis.
54 citations
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August 2005 in “Alcohol” Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.
9 citations
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February 2022 in “Biomedicines” Testosterone treatment may change estrogen receptor methylation in AFAB individuals.
11 citations
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July 2015 in “Journal of Anatomy” SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.
30 citations
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March 1980 in “European Journal of Endocrinology” Adrenal androgens are important for puberty and are influenced by genetics.
Higher nitric oxide synthase levels in the scalp may influence hair loss in androgenetic alopecia.
August 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” Testosterone and finasteride showed minor cognitive benefits in older men.
August 2022 in “Metabolites” Different types of skin on mice have unique chemical profiles related to how they grow and react to stress.
August 2024 in “JEADV Clinical Practice” Mesotherapy with dutasteride improves hair growth and reduces symptoms in frontal fibrosing alopecia.
25 citations
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April 2012 in “Acta Biomaterialia” Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.
26 citations
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September 2005 in “Pharmacology Biochemistry and Behavior” 5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.
9 citations
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January 2017 in “Archives of biochemistry and biophysics” Testosterone raises blood pressure and changes kidney protein levels.
10 citations
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June 1998 in “PubMed” Finasteride significantly reduces DHT levels in male dogs without affecting testosterone levels, suggesting it could be used to treat benign prostatic hypertrophy in dogs weighing 10 to 50 kilograms.
December 2025 in “Current Issues in Molecular Biology” New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
17 citations
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July 2015 in “Biomolecules and Biomedicine” High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.
3 citations
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October 1993 in “Endocrinology” 11 citations
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October 2020 in “General and comparative endocrinology” Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.
September 2011 in “Urology” Urinary PSA could be an early marker for enlarged prostate.
August 2023 in “Journal of Cosmetic Dermatology” Higher concentration of botulinum toxin A is safe and effective for treating hair loss in men and women.
December 2020 in “Benha Journal of Applied Sciences” Osteopontin levels are higher in people with androgenetic alopecia and are linked to metabolic disorders.