research Rare and common genetic determinants of metabolic individuality and their effects on human health
Genetic variations greatly affect individual metabolism and can impact health and disease risk.
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270-300 / 1000+ results research Therapeutic Potential of Brassinosteroids in Biomedical and Clinical Research
Brassinosteroids may be useful in treating cancer, infections, and other diseases.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research The effects of synthetic 19-norprogestins on osteoblastic cell function are mediated by their non-phenolic reduced metabolites
Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.
research Distribution of Body Hair in Young Australian Women and Associations With Serum Androgen Concentrations
More body hair in young Australian women is linked to higher androstenedione levels.
research Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and Metabolism
Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.
research A novel actor in skin biology: the mineralocorticoid receptor
Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.
research The association of medications and supplements with human male reproductive health: a systematic review
Some medications and supplements can affect male fertility, with some improving and others harming sperm quality.
research Active Antialopecia Chemical Identification of Merremia peltata Leaves and Computational Study toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation
Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.
research Hirsutism-A Comprehensive Update of Embryology, Aetiopathogenesis and Therapeutic Approach
The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
research Drugs and Androgenetic Alopecia: What to look out for
Certain drugs can worsen hair loss in people prone to androgenetic alopecia.
research The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
research The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder
Finasteride reduces opioid use and withdrawal symptoms in animals.
research The connection of 5-alpha reductase inhibitors to the development of depression
5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
research Localized alopecia and suppression of hypothalamic-pituitary-adrenal (HPA) axis in dogs following treatment with difluprednate 0.05% ophthalmic emulsion (Durezol®)
Long-term use of difluprednate eye drops in dogs can lead to hair loss and hormone imbalance.
research Pseudoglucagonoma syndrome secondary to pancreatitis: A case report
A young woman with skin issues and weight loss improved after treating her pancreatitis and using skin treatments.
research Hirsutism and Virilization in the Female
The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.
research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research Cutaneous sarcoidosis masquerading as papular amyloidosis revealed post--hair removal
Skin problems after waxing led to a sarcoidosis diagnosis.
research Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris
The best treatment for Frontal Fibrosing Alopecia and Lichen Planopilaris combines oral and topical medications to reduce symptoms and stop hair loss.
research Proceedings of the Ninth World Congress for Hair Research (2015)
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Novel Clove Essential Oil Nanoemulgel Tailored by Taguchi’s Model and Scaffold-Based Nanofibers: Phytopharmaceuticals with Promising Potential as Cyclooxygenase-2 Inhibitors in External Inflammation
Clove essential oil nanoemulgel effectively reduces skin inflammation and is a promising alternative to traditional anti-inflammatory drugs.
research Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production
Omega-6 fats in certain cells boost male hormone production.
research Genetic and other epidemiological risk factors of infants and children with hypospadias: a case control study
Older parental age, rural living, and specific genetic mutations increase hypospadias risk in children.
research Formulation and evaluation of self-nanoemulsifying drug delivery system for improved oral delivery of exemestane hydrochloride
The new drug delivery system improves exemestane's absorption and effectiveness.
research Autoimmunity: Alopecia Areata
Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.
research Sarcoidosis: Are there differences in your skin of color patients?
Sarcoidosis is more common and severe in Black patients than in Caucasians, requiring early diagnosis and treatment.
research The Search for the Causes of Common Hyperandrogenism, 1965 to Circa 2015
Significant progress was made in understanding androgen excess disorders, but much is still unknown.
research Fenugreek as a Versatile Cosmetic Ingredient: Phytochemical Profile, Skin–Hair Benefits and Formulation Opportunities
Fenugreek is a promising cosmetic ingredient for skin and hair care.
research Pharmacotherapy for Keloids and Hypertrophic Scars
Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.