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A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.

Effective management of hyperandrogenism in young women requires accurate diagnosis and tailored treatment.

Sporadic trichoblastic neoplasms generally don't recur or spread, with one case showing a specific genetic fusion.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.

Vorasidenib can cause unusual hair growth.

Hyperthyroidism can hide signs of high androgen levels in females.

A 25-year-old man had an unusual case of benign skin tumors and hair loss.

The patient had complex urinary tract issues and ambiguous genitalia, with physical features suggesting a hormonal imbalance.

Excessive male hormones in women cause symptoms like unwanted hair growth, and treatment requires careful medical evaluation.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

Hair loss in postmenopausal women due to ovarian hyperthecosis is rare, but removing the ovaries can significantly improve the condition.

A 70-year-old woman with a malignant adrenal tumor improved after surgery and radiotherapy.

A man developed a benign tumor at his COVID-19 vaccination site, which was successfully removed with surgery.

A 22-year-old woman with a rare genetic condition was successfully treated to develop normal female characteristics and regular menstruation.

A unique type of complex cyst was found on a man's scrotum.

TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.

Hirsutism is excessive male-pattern hair growth mainly caused by ovarian hormones, and severe cases may require costly treatment with side effects.

The man's symptoms improved and the tumor shrank after treatment with cabergoline.

A woman developed male traits from accidental contact with her husband's testosterone gel.

The nodule on the woman's back was a benign hair follicle tumor, not cancer, but needed removal.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

Women with pituitary adenomas often have reproductive issues, like irregular periods and trouble getting pregnant, but not always breast milk production without pregnancy.