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research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route
Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.
research Characterization of spironolactone and metabolites derivatized using Girard's reagent P using mass spectrometry and ion mobility spectrometry
Girard's reagent P improves detection of spironolactone and its metabolites.
research TRPV Channels in Osteoarthritis: A Comprehensive Review
TRPV channels are important in osteoarthritis and could be key to new treatments.
research Sulfur Containing Tyrosine Analogs Can Cause Selective Melanocytotoxicity Involving Tyrosinase-Mediated Apoptosis
research Rapid determination and quantification of hair-growth compounds in adulterated products by ultra HPLC coupled to quadrupole-orbitrap MS
About 21% of tested hair loss supplements contained illegal synthetic drugs.
research New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors.
Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
research Attempted construction of minoxidil: carboxylic acid cocrystals; 7 salts and 1 cocrystal resulted
Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
research Tocopherol contents and antioxidant activity in grape pomace after fermentation and alcohol distillation
Grape pomace can be used to make valuable products with antioxidants and tocopherols.
research Pharmacological Review on Purification of Visha Dravyas (Poisonous Plants) According to Ayurveda
Ayurveda can make poisonous plants medicinal through specific purification processes.
research Effects of Solvent System and Storage Condition on Chemical Stability of 5(alpha)-Reductase Inhibitor Compounds in Tectona grandis L.f. Leaf Extracts
Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.
research Synthesis of N-Substituted 3-Oxo-17b- carboxamide-4-aza-5a-androstanes and the Tautomerism of 3-Oxo-4-aza-5-androstenes
Researchers made two new compounds that could be used for medicine.
research Chemical Reactions Occurring in Curing Treatment for Permanent Hair Straightening Using Thioglycolic and Dithioglycolic Acids
Using both TGA and DTDG in hair straightening reduces hair damage compared to using TGA alone.
research Pleural Effusion Associated With Divalproex Sodium
Divalproex sodium can cause pleural effusion, which stops when the drug is discontinued.
research The effect of Cotinus coggygria L. ethanol extract in the treatment of burn wounds
Cotinus coggygria extract cream may help heal burn wounds.
research The Suppression of Very Long Chain Fatty Acids Is Associated with Skin Carcinogenesis
Suppressing very long chain fatty acids is linked to skin cancer.
research Effect of Hydroxypropyl Methylcellulose (HPMC) in Release Profile of Air Fresheners Gel Prepared Using Carrageenan and HPMC
The F2 Emulgel with Tridax procumbens extract showed good physical properties and antimicrobial effectiveness for wound healing.
research Discovering the potential of natural remedies in the post COVID-19 complications based on in silico techniques
Natural compounds, especially Withaferin-A, may help treat post-COVID-19 complications, but some may have side effects.
research TOXICOLOGICAL STUDY ON THE HEALTH EFFECTS OF LONG TERM EXPOSURE TO BENZENE IN BENZENE FILLING WORKERS, QASSIM REGION, KSA
Long-term exposure to benzene increases skin diseases, blood disorders, and liver problems.
research Environmental exposure to platinum group elements released by automotive catalytic converters: the risk for children
Children are at risk of health issues from exposure to platinum group elements from car exhausts.
research Acute Toxicity Evaluation of Ficus Platyphylla Methanolic Leaf Extract on Wistar Rats
Ficus platyphylla leaf extract is likely safe in high doses, with minor temporary side effects.
research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior
The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
research Counterfeit drugs and pharmaceutical preparations seized from the black market among bodybuilders
Many black market drugs for bodybuilders are fake and mislabeled.
research Do Syrian conflict survivors show novel chronic cutaneous sequelae from chlorine gas exposure: A case report and literature review
Chlorine gas exposure can cause long-term skin issues.
research Lipolytic agents for submental fat reduction: Review
Deoxycholic acid is FDA-approved for reducing submental fat, but its mechanisms are not fully understood.
research The First Syntheses of 16β-Chloro- and 16β-Bromo-cyproterone Acetate
Scientists made two new chemicals that might help treat diseases caused by male hormones.
research THE CHEMISTRY MECHANISM OF HAIR DYES
Permanent hair dyes use chemicals that react with hydrogen peroxide to create color.
research Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum production
Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
research Contents list
research GC-MS analysis and phytochemical screening of methanolic fruit extract of Citrullus colocynthis (L.) Schrad
The methanolic fruit extract of Citrullus colocynthis contains bioactive compounds that may support its use in traditional medicine and drug development.