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420-450 / 1000+ resultsresearch The Role of the TRPV4 Channel in Intestinal Physiology and Pathology
Targeting the TRPV4 channel may help treat intestinal diseases.
research Peripheral patterns of calcitonin‐gene‐related peptide general somatic sensory innervation: Cutaneous and deep terminations
CGRP-IR axons may help maintain and renew tissues.
research Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Visual imaging of calcium ion distribution in acetone and tape stripping damaged canine epidermis.
The method visualized calcium ions in damaged canine skin, showing potential for studying skin recovery.
research Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists
Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
research Investigations into the roles of potassium channels in hair growth : studies confirming the presence of several ATP-sensitive potassium (K+ATP) channels in hair follicles and exploring their mechanism of action using molecular biological, cell culture, organ culture and proteomic approaches
KATP channels are crucial for hair growth, and targeting them may lead to new hair loss treatments.
research TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons
TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
research TRPV1 Function in Health and Disease
TRPV1 is involved in pain, various body functions, and diseases, but targeting it for treatment is challenging.
research 2‐Deoxy‐d‐glucose enhances tonic inhibition through the neurosteroid‐mediated activation of extrasynaptic GABAA receptors
2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
research A ‘hot’ new twist to hair biology – involvement of vanilloid receptor‐1 signaling in human hair growth control
VR1 signaling can inhibit hair growth by affecting cell processes and increasing hair growth inhibitors.
research Ca 2+ -mediated protein citrullination regulates proliferation in the regenerating and malignant CNS
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
research Localization of mechanosensitive channel TRPV4 in mouse skin
TRPV4 helps sense pressure in mouse skin.
research Overexpression of the calcium sensing receptor accelerates epidermal differentiation and permeability barrier formation in vivo
Increasing calcium sensing receptor speeds up skin and hair development in mice.
research Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch
Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.
research Close Temporal Relationship between Oscillating Cytosolic K+ and Growth in Root Hairs of Arabidopsis
Potassium changes lead root hair growth, with calcium and other factors regulating the process.
research 피부장벽, 이온, 사이토카인
Calcium is crucial for skin development and healing.
research Hormonal Control of Cardiac Action Potential Phase 1 Currents in the Brugada Syndrome
Androgens may increase arrhythmias in Brugada Syndrome, while Finasteride could reduce them.
research Ultrastructural Localization and Quantification of Extracellular Calcium Binding Sites in Mouse Vibrissa and Human Scalp Follicles
Hair growth drugs and epidermal growth factor do not change the calcium binding site gradient in hair follicles.
research Editor's evaluation: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)
CCC1 is crucial for pH balance in plant cells, affecting growth and stress tolerance.
research TRPV Channels in Osteoarthritis: A Comprehensive Review
TRPV channels are important in osteoarthritis and could be key to new treatments.
research Catamenial-like seizure exacerbation in mice with targeted ablation of extrasynaptic δGABA-a receptors in the brain
Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.
research Effect of minoxidil sulfate and pinacidil on single potassium channel current in cultured human outer root sheath cells and dermal papilla cells
Minoxidil sulfate and pinacidil may promote hair growth through increased blood flow, not by activating potassium channels.
research CFTR potentiator ivacaftor protects against noise-induced hair cell loss by increasing Nrf2 and reducing oxidative stress
Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.
research The Relationship Between Glycine and Gephyrin in Synapses of the Rat Spinal Cord
Glycine is a key transmitter in rat spinal cord synapses, often alongside GABA.
research G2 stem cells orchestrate time-directed, long-range coordination of calcium signaling during skin epidermal regeneration
G2 stem cells control calcium signaling for skin regeneration.
research Decision letter: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)
CCC1 is essential for ion balance and proper plant cell function.
research Author response: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)
CCC1 is essential for pH balance and normal cell function in plants.
research [Visual field defect in a patient given sodium valporate then carbamazepine: possible effect of aminotransferase inhibition].
Anti-epileptic drugs may cause visual and hair side effects due to enzyme inhibition, especially in genetically predisposed individuals.
research Obituary: Professor Edward Carmeliet 1930 – 2021
Professor Edward Carmeliet was a leading figure in cardiac electrophysiology research.