32 citations
,
July 2001 in “Endocrine Practice” Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
30 citations
,
October 2005 in “Journal of Investigative Dermatology Symposium Proceedings” The document concludes that hair transplantation is recommended for those not helped by medical treatments, but warns that high-density transplants may lower hair survival rates.
30 citations
,
May 1980 in “Journal of the American Academy of Dermatology” Alopecia areata can cause spotty white areas on nails.
28 citations
,
November 2007 in “Medical Clinics of North America” Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.
26 citations
,
February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
26 citations
,
June 2000 in “Journal of The American Academy of Dermatology” Men with balding at age 45 had higher IGF-1 and lower IGFBP-3, suggesting these factors might be important in male pattern baldness.
26 citations
,
May 1984 in “Journal of Parenteral and Enteral Nutrition” Biotin supplements restored hair and resolved symptoms in a woman with biotin deficiency.
22 citations
,
January 1985 in “Journal of Human Evolution/Journal of human evolution” Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
21 citations
,
December 2007 in “Primary Care” Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
21 citations
,
January 2000 in “Fetal Diagnosis and Therapy” Prenatal diagnosis of trichothiodystrophy is possible in the second trimester using fetal eyebrow biopsy, with sulfur content analysis being more reliable.
18 citations
,
March 2010 in “Gynecologic and obstetric investigation” The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.
17 citations
,
February 1987 in “Journal of the American Academy of Dermatology” The hair cuticle acts as a barrier against fungal infection, which occurs only deep within the hair follicle.
16 citations
,
September 2018 in “Journal of Molecular Liquids” The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.
16 citations
,
April 2007 in “Journal of Medical Primatology” The monkey's hair loss was due to an autoimmune disease, not genetics.
16 citations
,
January 2006 in “The Aging Male” Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
13 citations
,
January 2013 in “Dermatologic Surgery” Experienced hair transplant surgeons suggest a limited number of hair follicles can be used for transplants, and recommend conservative methods to avoid scarring and depletion.
13 citations
,
May 2004 in “Dermatologic Surgery” The paper concludes that copying the natural direction and angle of hair in transplants is key for a natural look and doesn't harm hair survival.
12 citations
,
November 2012 in “BioMolecular Concepts” PPAR β/δ is important for skin health and disease treatment, but more research is needed.
11 citations
,
March 2014 in “Journal of Investigative Dermatology” Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
10 citations
,
April 2013 in “Revista cubana de plantas medicinales” Sida cordifolia L. is rich in saponins with antioxidant and antifungal properties.
10 citations
,
January 2004 in “Dermatologic Surgery” Storing hair follicles in special buffers with added protective substances can increase hair growth and reduce cell death.
8 citations
,
January 2007 in “Hair transplant forum international” Vitamin B12 improves the health and growth of hair micrografts.
8 citations
,
May 2003 in “Hair transplant forum international” New storage solutions improve the survival of small hair grafts and results of hair transplant surgeries.
7 citations
,
July 2023 in “Immunotherapy” Ritlecitinib works well and is safe for treating alopecia areata.
7 citations
,
June 2004 in “Dermatologic Surgery” A new hair transplant method combines individual and group follicles for better results and efficiency.
7 citations
,
June 1992 in “The Journal of Dermatologic Surgery and Oncology” Hair transplantation is a viable treatment for some types of female hair loss, with careful donor assessment and attention to psychological factors.
7 citations
,
March 1990 in “Pigment Cell Research” Certain chemicals cause hair graying in black mice but not yellow mice.
7 citations
,
January 1990 Spironolactone improved hair density and quality in women with hair loss.
7 citations
,
December 1984 in “The Journal of Dermatologic Surgery and Oncology” Early transplantation helps avoid embarrassment and allows relaxed transplant sessions, but be cautious with young patients with thinning hair.
6 citations
,
February 2023 in “Advances in Therapy” Baricitinib, a drug for rheumatoid arthritis, atopic dermatitis, and alopecia areata, is generally safe with low risk of major side effects, even in patients with risk factors. It's also effective in promoting hair regrowth in alopecia areata patients.