research Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation
N-WASP is essential for healthy skin and preventing inflammation.
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research Treatment of alopecia areata in pre‐adolescent children with oral tofacitinib: A retrospective study
Oral tofacitinib may effectively treat hair loss in children with alopecia areata.
research Male pattern baldness and its association with coronary heart disease: a meta-analysis
Severe baldness on the top of the head is linked to a higher chance of heart disease, especially in men under 60.
research Biochemistry of epidermal stem cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
research Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
research Testosterone levels in relation to oral contraceptive use and the androgen receptor CAG and GGC length polymorphisms in healthy young women
Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.
research Thyroid diseases and skin autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Lifestyle and Physiological Factors Associated with Facial Wrinkling in Men and Women
Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.
research Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study
Women with androgenetic alopecia experience worse physical well-being and quality of life, but similar mental health compared to those without it.
research Group IID, IIE, IIF and III secreted phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system
Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
research Dehydroepiandrosterone for women in the peri- or postmenopausal phase
DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
research Contribution of hair density and hair diameter to the appearance and progression of androgenetic alopecia in Japanese men
Hair thickness matters more than density for baldness in Japanese men over 25.
research Prevalence of cervical insufficiency in polycystic ovarian syndrome
Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.
research Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling
Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
research Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis
5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
research Defining hyperandrogenaemia according to the free androgen index in Chinese women: a cross-sectional study
FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.
research Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-epithelization and Epidermal Growth
HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
research Twenty-Five and Up (25Up) Study: A New Wave of the Brisbane Longitudinal Twin Study
The 25Up study collected extensive data on mental disorders and related factors in Australian twins and siblings to investigate the genetics of psychiatric illnesses.
research Perspectives on Hair Evolution Based on Some Comparative Studies on Vertebrate Cornification
Hair in mammals likely evolved from glandular structures, not scales.
research Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats
A new therapy sped up wound healing and reduced scarring in diabetic rats.
research Association of type 2 diabetes with central-scalp hair loss in a large cohort study of African American women
Type 2 diabetes may increase the risk of severe hair loss in African American women.
research Determining the normal cut-off levels for hyperandrogenemia in Chinese women of reproductive age
Normal levels for certain hormones in Chinese women of reproductive age were identified.
research Increased risk of fractures in patients with polycystic ovary syndrome: a nationwide population-based retrospective cohort study
Women with polycystic ovary syndrome have a higher risk of certain fractures.
research Efficacy of Cistanche Tubulosa and Laminaria Japonica Extracts (MK-R7) Supplement in Preventing Patterned Hair Loss and Promoting Scalp Health
MK-R7 supplement with Cistanche Tubulosa and Laminaria Japonica extracts improved hair density and scalp health without adverse effects.
research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
research Gut microbiota in alopecia areata
Alopecia areata may be linked to imbalanced gut bacteria.
research Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells
An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.
research Systematic review of low-level laser therapy for adult androgenic alopecia
Low-level laser therapy can stimulate hair growth more effectively than fake devices, but patient satisfaction is similar for both. Results should be taken with caution due to small study sizes and differences between studies. More research is needed.
research Cultural Sensitivity and Challenges in Management of the Transgender Patient With ESRD in Transplantation
Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.