December 2021 in “Indian Journal of Dermatology, Venereology and Leprology” Men with androgenetic alopecia, or hair loss, often have abnormal blood flow in their small blood vessels, which might be linked to inflammation and stress.
September 2020 in “Zenodo (CERN European Organization for Nuclear Research)” Reducing Zyxin may help treat hair loss.
March 2020 in “Journal of Laser Applications” Photobiomodulation therapy significantly increases hair density and growth for androgenic alopecia, but more research is needed to confirm safety.
September 2014 in “Chinese Journal of Dermatology” Hair diameter difference, brown skin discoloration around hair follicles, and missing hair in certain areas are key signs of androgenetic alopecia (commonly known as hair loss) when viewed under a dermoscope.
April 2012 in “The Journal of Urology” Early baldness increases prostate cancer risk, radiotherapy and surgery have similar second cancer rates, and ALA may reduce prostate cancer risk.
September 2005 in “Archives of Dermatological Research” Large prostate patients more likely to have hair loss.
556 citations
,
September 2008 in “Genes & Development” Wnt signaling is vital for cell growth, development, and cancer research.
297 citations
,
December 2005 in “Journal of controlled release” P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
212 citations
,
May 2012 in “Genes & Development” Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
192 citations
,
April 2019 in “ACS nano” A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.
181 citations
,
January 2009 in “Nature Genetics” Certain mutations in a hair growth-related gene cause a type of genetic hair loss.
91 citations
,
March 1996 in “Archives of Dermatological Research” Certain cytokines and growth factors can inhibit hair growth and may affect alopecia areata.
89 citations
,
December 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” Human hair can be used to measure reproductive hormones.
87 citations
,
March 2017 in “Journal of Clinical Investigation” PSENEN gene mutations can cause both Dowling-Degos disease and acne inversa.
73 citations
,
June 2010 in “PLoS Genetics” A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
63 citations
,
March 2016 in “International Journal of Molecular Sciences” Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.
61 citations
,
February 2003 in “Experimental Dermatology” Soy oil and genistein reduce hair loss risk in mice.
59 citations
,
August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
59 citations
,
May 2017 in “Scientific reports” ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.
59 citations
,
December 2016 in “Supportive Care in Cancer” Core symptoms in breast cancer chemotherapy remain stable, aiding targeted interventions.
56 citations
,
December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
52 citations
,
May 2015 in “Cytotherapy” DS-MSCs from hair follicles may improve diabetic wound healing.
48 citations
,
September 2011 in “British Journal of Dermatology” Epigenetic changes in blood cells may contribute to alopecia areata.
45 citations
,
January 2021 in “Stem Cell Research & Therapy” The combination of stem cell medium and hydrogel effectively reduces and improves hypertrophic scars.
44 citations
,
March 2019 in “Experimental Dermatology” A wide range of proteins are integrated into the skin's protective layer.
43 citations
,
August 2016 in “International Journal of Nanomedicine” Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
43 citations
,
January 2016 in “Oxidative medicine and cellular longevity” THSG from a Chinese plant helps with aging and related diseases.
43 citations
,
July 2017 in “International journal of pharmaceutics” Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.
43 citations
,
January 2006 in “PubMed” Androgens and estrogens are crucial for male reproductive health, affecting hormone levels and tissue function.
38 citations
,
October 2014 in “British journal of dermatology/British journal of dermatology, Supplement” Bimatoprost solution is effective and safe for long-term use in treating eyelash thinning.