November 2021 in “Current Otorhinolaryngology Reports” New treatments for hair loss could involve using stem cells and a process called the Wnt/beta-catenin pathway to stimulate hair growth.
21 citations
,
January 2018 in “Journal of Investigative Dermatology” Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
13 citations
,
October 2020 in “BMC Genomics” Long non-coding RNAs play a key role in yak hair growth cycles.
7 citations
,
January 2019 in “PeerJ” A protein called sFRP4 can slow down hair regrowth.
1 citations
,
October 2025 in “International Journal of Molecular Sciences” Mutating the gmds gene in zebrafish increases hair cell numbers and regeneration.
April 2025 in “Journal of Ethnopharmacology” Amygdalin in Persicae Semen may help treat hair loss by promoting hair growth and regulating key pathways.
January 2026 in “International Journal of Molecular Sciences” Understanding molecular signals and genetics is key to improving hair regeneration therapies.
6 citations
,
November 2022 in “Development” New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
9 citations
,
August 2024 in “International Journal of Molecular Sciences” Promising treatments for EBS include anti-inflammatory drugs, antibiotics, creams, mTOR inhibitors, and gene editing, but more trials are needed.
8 citations
,
March 2015 in “Molecular Medicine Reports” Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.
Understanding hair follicle interactions can help treat male pattern baldness.
May 2025 in “Journal of Craniofacial Surgery Open” High-intensity focused ultrasound improved hair growth in a woman with no side effects.
733 citations
,
September 2009 in “Journal of Cell Science” Wound healing is a complex, multi-phase process involving various cells and activities to repair skin damage.
115 citations
,
December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
105 citations
,
April 2014 in “Trends in Pharmacological Sciences” Targeting the Smoothened receptor shows promise for treating certain cancers.
81 citations
,
September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.
44 citations
,
June 2017 in “The EMBO Journal” LPA3 signaling in the uterus is crucial for placental formation and fetal development.
43 citations
,
December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
37 citations
,
May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
31 citations
,
September 2012 in “Journal of biological chemistry/The Journal of biological chemistry” The right amount of retinoic acid is essential for normal hair growth and development.
22 citations
,
June 2024 in “Cell” Understanding tissue self-organization can improve treatments for diseases and advance regenerative medicine.
5 citations
,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
5 citations
,
April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
2 citations
,
February 2025 in “International Journal of Molecular Sciences” Key proteins and pathways regulate yak hair growth, with lipid metabolism aiding adaptation to high altitudes.
February 2026 in “International Journal of Molecular Sciences” Silencing SFRP1 alone promotes hair growth, but adding DKK1 does not help.
January 2026 in “Current Issues in Molecular Biology” FGF-7 helps hair grow by activating hair follicles and is a promising target for hair loss treatments.
September 2024 in “Stem Cell Research & Therapy” HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.
2 citations
,
July 2019 in “PeerJ” Removing the VDR gene in skin cells reduces their growth and affects hair-related genes.
15 citations
,
December 2020 in “International journal of molecular sciences” Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
November 2023 in “Materials Today Bio” The new treatment using nanoparticles with ISX9 can effectively regrow hair without major side effects.