14 citations
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September 1999 in “Journal of Investigative Dermatology” Lack of TrkC receptor delays hair follicle development.
24 citations
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December 2013 in “Archives of Dermatological Research”
April 2017 in “Journal of Investigative Dermatology” Dermal Wnt/β-catenin signaling is important for the proper size and development of hair follicles.
January 2026 in “Frontiers in Pharmacology” Anwuligan may help treat hair loss by promoting hair growth.
July 2023 in “Current Issues in Molecular Biology” Escin may help treat hair loss by boosting a specific cell growth pathway.
4 citations
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March 2018 in “Animal biotechnology” The LAMTOR3 gene is involved in cashmere goat hair growth and is affected by certain treatments and other genes.
6 citations
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October 2012 in “Journal of Heredity” The Itpr3 gene causes a specific hair pattern in mice.
22 citations
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March 2019 in “The Journal of Cell Biology” The Wave complex controls skin growth by suppressing certain signals.
3 citations
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November 2015 in “Journal of Investigative Dermatology” Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
176 citations
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January 2013 in “Proceedings of the National Academy of Sciences” BMP and Wnt signaling balance controls hair follicle stem cell activity and hair growth.
555 citations
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July 2001 in “Genes & Development” Tcf3 and Lef1 are key in deciding skin stem cell roles.
13 citations
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November 2022 in “BMB Reports” Wnt/β-catenin activators can help regrow hair lost due to diabetes.
March 2026 in “Stem Cell Reviews and Reports” 24 citations
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March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
326 citations
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February 2009 in “The American journal of pathology” Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
May 2024 in “Cell proliferation” Melatonin helps hair grow by activating a specific signaling pathway.
62 citations
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December 2007 in “Journal of Cellular and Molecular Medicine” Kremen is crucial for proper development and preventing tumors by regulating Wnt signaling.
31 citations
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October 2010 in “Progress in lipid research” LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
January 2004 in “Giornale di Metafisica: revista bimestrale di filosofia” Increased Wnt signaling causes hair graying by depleting melanocyte stem cells in aged mice.
January 2026 in “PLoS Biology” ARHGEF3 is essential for proper hair follicle development in mice.
41 citations
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August 2015 in “The FASEB Journal” Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
44 citations
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June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
18 citations
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July 2023 in “International Journal of Molecular Sciences” KY19382 speeds up wound healing by activating a specific cell signaling pathway.
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Telocytes, cells with long extensions, are vital for hair growth because they produce Wnt signals, which are necessary for hair follicle regeneration.
February 2026 in “International Journal of Molecular Sciences” 3-Hydroxypropionic acid may help treat hair loss by promoting hair growth in cells.
75 citations
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April 2000 in “Developmental Dynamics” Whn is essential for hair growth, and its malfunction causes hair loss.
July 2026 in “Pathology - Research and Practice”
October 2021 in “Journal of Investigative Dermatology” Dkk4 protein is necessary for the proper development and arrangement of hair follicles.
4 citations
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December 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.