April 2019 in “Journal of Investigative Dermatology” Calcium signals and SHH guide the direction of feather growth in chicken skin.
150 citations
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December 2012 in “EMBO Reports” Stem cell self-renewal is complex and needs more research for full understanding.
102 citations
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April 2014 in “PloS one” Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
28 citations
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June 2020 in “ACS Biomaterials Science & Engineering” The new ECM patch greatly improves wound healing and tissue regeneration.
January 2016 in “Minerva Access (University of Melbourne)” Hair follicle transplantation can improve wound healing and nerve growth.
721 citations
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October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
170 citations
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November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
132 citations
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June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
36 citations
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September 2013 in “PLoS ONE” Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
16 citations
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August 2019 in “Journal of the Chinese Medical Association” Stem cell therapy could improve burn healing but has challenges to overcome.
9 citations
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November 2021 in “Current Opinion in Genetics & Development” Wounds can cause new hair growth in adult mice, influenced by Wnt signaling.
5 citations
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September 2022 in “Journal of Investigative Dermatology” Careful selection of mice by genetics and age, and controlled housing conditions improve the reliability of hair regrowth in wound healing tests.
2 citations
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May 2024 in “Immunity” Stem cells help control the immune response to improve wound healing.
2 citations
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January 2022 in “Experimental Dermatology” GDNF signaling helps in hair growth and skin healing after a wound.
Inhibiting IL-17 and IL-23 improves wound healing in obese, diabetic mice by promoting healing macrophages.
November 2025 in “Journal of Investigative Dermatology” Hair follicle stem cells help maintain skin health after injury.
June 2021 in “Research Square (Research Square)” The exact identity of skin stem cells and how skin cells differentiate is not fully known.
908 citations
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July 2015 in “British Journal of Dermatology” Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
333 citations
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February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
306 citations
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April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
291 citations
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April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
254 citations
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January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
137 citations
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April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
92 citations
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September 2015 in “Journal of Lipid Research” Skin fat helps with body temperature control and has other active roles in health.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
63 citations
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April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
60 citations
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June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.
58 citations
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November 2013 in “Journal of Innovative Optical Health Sciences” Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
51 citations
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March 2019 in “Journal of cellular physiology” Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
44 citations
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June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.