144 citations
,
December 2017 in “Pigment cell & melanoma research” Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.
February 2025 in “International Journal of Research Publication and Reviews” Butterfly pea flower is valued for its health benefits, color-changing ability, and use in food and drinks.
18 citations
,
March 2015 in “Journal of Investigative Dermatology” Silencing certain circadian clock genes increases skin pigmentation.
14 citations
,
September 2017 in “General and comparative endocrinology” Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.
9 citations
,
March 2022 in “Antioxidants” Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
5 citations
,
January 2016 in “European Journal of Dermatology” Suplatast tosilate successfully treated a woman's systemic sclerosis symptoms.
2 citations
,
April 2021 in “International Journal of Cosmetic Science” The sunscreen with two antioxidants offers quick and lasting skin protection from sun damage.
16 citations
,
January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
November 2011 in “Journal of Investigative Dermatology” TRH in hair follicles can influence hair color by increasing melanin.
12 citations
,
September 2018 in “International Journal of Cosmetic Science” Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
2 citations
,
September 2022 The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.
Azelaic acid helps with skin pigmentation issues, but its full effects are not completely understood.
August 2018 in “Pediatric Dermatology” A baby had a unique skin condition with a pale patch and surrounding dark hairs, not linked to other health issues.
3 citations
,
February 2024 in “International journal of molecular sciences” Hesperidin from orange peels is a promising natural ingredient for skincare due to its multiple beneficial properties.
182 citations
,
November 2018 in “Cosmetics” Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.
83 citations
,
August 2020 in “Resources” Macroalgae compounds offer sustainable, effective benefits for cosmetics.
19 citations
,
July 2024 in “Journal of Cellular and Molecular Medicine” Astaxanthin may reduce inflammation in women with PCOS, but doesn't significantly improve symptoms.
18 citations
,
December 2021 in “Foods” Seaweeds contain beneficial compounds with potential uses in food, cosmetics, and health, but more research is needed to improve extraction and safety.
12 citations
,
December 2023 in “Antioxidants” Blackberry leaves have stronger antioxidant properties than raspberry leaves.
6 citations
,
April 2025 in “Frontiers in Sustainable Food Systems” Transforming vegetable waste into valuable ingredients can support sustainability and economic growth.
6 citations
,
May 2022 in “Frontiers in Microbiology” Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.
5 citations
,
April 2024 in “Heliyon” Wild and cultivated Saccharina latissima differ in chemical makeup and color due to environmental factors.
2 citations
,
September 2025 in “Food Production Processing and Nutrition” Capsaicin offers health benefits and flavor but faces challenges in food use.
March 2026 in “Journal of Cosmetic Dermatology” Keratinocyte Growth Factor-Hair Serum may help prevent hair loss during chemotherapy, but more research is needed.
December 2025 in “Cosmetics” Nanocarriers can improve skin treatments after cancer therapy by enhancing antioxidant delivery and effectiveness.
January 2025 in “Pharmaceuticals” Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.
2 citations
,
October 2016 in “Nutrition in clinical practice” Vitamin B12 deficiency can cause facial dark spots that go away with treatment.
34 citations
,
August 2002 in “British Journal of Dermatology” ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.
April 2016 in “Journal of Investigative Dermatology” Vitamin D can reduce skin inflammation caused by UV rays by enhancing cell "fitness" and skin repair.