402 citations
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August 2011 in “Cancer research” Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
8 citations
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October 1989 in “International Journal of Dermatology” Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
18 citations
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November 2013 in “Molecules and Cells” New culture method keeps human skin stem cells more stem-like.
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” The Enriched-GF method efficiently produces high-yield growth factors for tissue repair.
November 2025 in “Frontiers in Immunology” Immune cells are crucial for normal skin development and their dysfunction can cause skin disorders.
July 2025 in “International Journal of Pharmaceutical Research and Development” Exosomes can improve skin treatments with fewer side effects.
522 citations
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January 2001 in “Cancer investigation” Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
18 citations
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September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
25 citations
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April 2008 in “Archives of Dermatological Research” Encapsulated human hair cells can substitute for natural hair cells to grow hair.
19 citations
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April 2016 in “Experimental Dermatology” Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.
77 citations
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August 2025 in “Signal Transduction and Targeted Therapy” Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
1 citations
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November 2025 in “Cell Death and Disease” Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.
January 2026 in “Asian Journal of Pharmaceutical and Clinical Research” Umbilical cord and cord blood stem cells are promising for treating chronic diseases due to their versatility and ethical acceptability.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
70 citations
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August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
69 citations
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June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
29 citations
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December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
22 citations
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January 2014 in “Biological & Pharmaceutical Bulletin” Ginsenoside F2 may help prevent hair loss and promote hair growth better than finasteride.
9 citations
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December 2020 in “International Journal of Medical Sciences” iPSCs help understand and treat neurodevelopmental disorders.
7 citations
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February 2018 in “InTech eBooks” Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.
6 citations
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December 2021 in “Scientific Reports” Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
1 citations
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January 2024 in “Nature communications” Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
1 citations
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September 2022 in “Morphology” Human stem cells have diverse sources and potential uses in medicine.
Hair follicle-derived sheets can effectively treat vitiligo by repigmenting skin.
January 2026 in “Journal of Biomedical Research” Small extracellular vesicles from stem and immune cells show promise for treating various diseases but face challenges in clinical use.
December 2025 in “International Journal of Pharmacology” iPSC-derived artificial platelets show promise for consistent and effective regenerative therapies.
Mesenchymal stem cell-derived exosomes significantly increase hair density and thickness in androgenic alopecia patients.
September 2019 in “Journal of Investigative Dermatology” Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.