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Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

Anti-androgen drugs can treat conditions like prostate cancer and male pattern baldness by blocking effects of testosterone and DHT.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.

Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.

Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

New genes and pathways are important for testosterone production and male sexual development.

Estrogens and androgens are crucial for male fertility.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Finasteride exposure harms tadpole reproduction and hormone balance.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.