research Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals
Deleting TNFα gene reduces skin cancer risk in certain mice.
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780-810 / 1000+ resultsresearch Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats
Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.
research INHIBITION OF KERATINIZING STRUCTURES BY SYSTEMIC DRUGS
Some drugs can cause hair loss and skin issues.
research Evaluation of ameliorative efficiency of vitamin E and Saccharomyces cerevisiae yeast on arsenic toxicity in Black Bengal kids
Vitamin E, alone or with yeast, helped reduce arsenic poisoning effects in young goats.
research Toxic epidermal necrolysis caused by etonogestrel implantation: A rare presentation
A woman developed a severe skin reaction after getting a birth control implant.
research Excess dietary zinc causes hair loss and suppresses the immune response in second generation mice
Too much zinc can cause hair loss and weaken the immune system.
research How Biotin Induces Misleading Results in Thyroid Bioassays: Case Series
Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.
research Toxicity of repeated oral intake of organic selenium, inorganic selenium, and selenium nanoparticles: A review
Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.
research Modeling of chronic radiation-induced cystitis in mice
Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
research The pregnant urologist
Pregnant female urologists should avoid certain drugs and use protective measures to stay safe.
research The Pathogenesis of Oxidative Stress in Androgenetic Alopecia
Oxidative stress damages hair follicles and worsens hair loss in androgenetic alopecia.
research O-21 FROM ORAL LEVOTHYROXINE RESISTANCE TO INTRAVENOUS LEVOTHYROXINE HYPERSENSITIVITY: A CHALLENGING PRIMARY HYPOTHYROIDISM CASE
A woman with hypothyroidism developed an allergy to IV levothyroxine after being resistant to oral forms.
research Beneficial Effects of Liver on Cortisone Acetate Toxicity in the Rat.
Liver in the diet reduces cortisone acetate toxicity effects in rats.
research Low Intensity Ultrasound as an Antidote to Taxane/Paclitaxel-induced Cytotoxicity
Low intensity ultrasound may reduce side effects of chemotherapy drugs like paclitaxel.
research Xinyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6
Xinyang Tablet improves heart function in sepsis by reducing inflammation.
research ISID1403 - Melatonin protects K15+ human hair follicle stem cells against paclitaxel-induced damage ex vivo
Melatonin may protect hair follicle stem cells from damage caused by chemotherapy.
research The Case Files
Thyroid storm is hard to diagnose due to vague symptoms but needs urgent attention.
research Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Clinical Management of Cutaneous Adverse Events in Patients on Chemotherapy: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology
Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.
research Chronic toxicity of 3,4,3′,4′-tetrachlorobiphenyl in the marmoset monkey (Callithrix jacchus)
High doses of TCB cause severe health issues in marmoset monkeys.
research Witnessed trauma exposure induces fear in mice through a reduction in endogenous neurosteroid synthesis
Reduced neurosteroid production increases fear in mice, suggesting potential PTSD treatments.
research The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products
Psychotropic drugs can interact with natural products, affecting their effectiveness and safety.
research Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetradecanoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate
TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.
research Mixture effects of endocrine disrupting compounds in vitro
Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.
research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
research Expression Profiles of Reproduction- and Thyroid Hormone-Related Transcripts in the Brains of Chemically-Induced Intersex Frogs
Intersex frogs have different brain gene activity related to sex and thyroid hormones.
research Study on the mechanism of cadmium chloride pollution accelerating skin tissue metabolism disorder, aging and inhibiting hair regeneration
Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
research Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice
FoxN1 overexpression in young mice harms immune cell and skin development.
research Copper−Doxorubicin as a Nanoparticle Cargo Retains Efficacy with Minimal Toxicity
Copper-doxorubicin nanoparticles effectively treat tumors with less toxicity.
research A novel derivative of doxorubicin, AD198, inhibits canine transitional cell carcinoma and osteosarcoma cells in vitro
AD198 is more effective than doxorubicin in stopping certain dog cancer cells.