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Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

A new compound was made that might help treat diseases related to male hormones.

New compounds may help treat prostate cancer by reducing cell growth.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

Oral JAK inhibitors are effective and safe for treating alopecia areata but may need ongoing use to keep results.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Antioxidants might help prevent pressure ulcers, but more research is needed to find effective ones.

Alopecia X causes hair loss in young plush-coated dogs and can be treated with various therapies, but hair may regrow and then fall out again.

The compound was successfully made and shows potential for treating prostate cancer.

Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Special fiber materials boost the healing properties of certain stem cells.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.